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Ch 28 Hematologicic
| Question | Answer |
|---|---|
| ANC stands for | Absolute Neutrophil Count- The amount of WBCs that are neutrophils |
| Cryoprecipitate | |
| Any precipitate that results from cooling. Describes a precipitate rich in coagulation factor VIII. | |
| Erythropoietin | Hormone secreted by kidney stimulating red blood cell synthesis |
| Granulocytopenia | Granulocyte number decrease. The granulocytes are neutrophils, eosinophils, and basophils. |
| Hemoglobin is… | The oxygen-carrying component of red blood cells |
| Hemophilia - | Hereditary coagulation disorder where the blood doesn’t clot normally |
| Hypoxia | Low oxygen |
| Idiopathic means | There’s no known cause |
| Hydrostatic pressure | The pressure exerted by a fluid due to the force of gravity |
| Lymphoid organ | A component of the system in which lymph circulates throughout the whole body |
| Osmosis- | Fluid diffusion in a membrane of the low concentrated solute,,, to a membrane of high concentrated solute to achieve equilibrium. |
| Polycythemia | |
| When the total cell mass of the blood increases | |
| Solute | The substance dissolved in another substance |
| Splenectomy | Surgical removal of spleen |
| Thrombocyte | Platelet |
| Von Willebrand Disease | Most common inherited bleeding disorder. Deficiency in the clotting protein, Von Willebrand’s factor |
| FerrouSul is indicated for? | Iron deficiency anemia Generic: Ferrous sulfate |
| Ferate | Ferric gluconate |
| For the Tx of leukemia what is the generic name for Gleevec and Trexall? | Imatinib Methotrexate |
| How much of blood is plasma? What’s inside of it? | 50%. Could consist of water, proteins, electrolytes and nutrients |
| Serum- | Plasma that has been allowed to clot |
| Plasma protein albumin, is good for | -Maintaining water and solute balances in the blood. -Albumin does not diffuse, therefore it transports solutes between blood and tissues. -Maintains osmotic pressure |
| What happens when osmotic pressure decreases? | Due to a Deficiency in albumin leading to fluid accumulation and edema |
| How long is a platelets life span? | Approximately 10 days |
| The main function of an erythrocyte is | Carry oxygen to tissues and organs |
| Which organ produces (hormone) erythropoietin? | The kidneys. Erythropoietin largely drives the production of red blood cells |
| What brand names are indicated for iron deficiency anemia ? | Slow Fe* ; FerrouSul* ROA- Oral Aux- administer with food Side effect- black stool |
| What is sometimes prescribed in combination with iron supplements for better iron absorption strategies? | Vitamin c |
| What’s ferrous gluconate? | Ferate * ROA-Oral |
| Which drug indicated for iron deficiency anemia is parenteral? | INFeD Ferrlecit Venofer |
| Polycythemia | Overproduction off RBCs |
| What drug class treats polycythemia ? | Myelosuppressive agents -they minimize the thrombosis risk |
| First line of defense for polycythemia is | Droxia* hydroxyurea ROA-Oral MO-inhibits DNA synthesis Aux- |