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bio ch. 13
| Term | Definition |
|---|---|
| chemical potential energy stored in | phosphate bonds (ATP, GTP) |
| potential energy stored in what form | reduced form (NADH , FADH) |
| Glycosis found in | cytosol of cell |
| reactants to products in glycoysis | 6C glucose to 2 pyruvate (3C) 2 NAD + to 2 NADH 2 ADP + 2Pi to 2ATP |
| citric acid cycle in | matrix of mitochondria |
| ETC and oxidative phosorylation across | inner mitochondria membrane |
| inputs of citric acid cycle | 2 acetyl CoA 3 NAD+ FAD GDP |
| outputs of citric acid cycle (from 1 acetyl group) | 2 CO2 3 NADH 1 FADH2 1 GTP |
| 1 acetyl CoA group consists of | 2 C + CoA |
| coenzyme A does what | delivers acetyl group to citric acid cycle enzyme that adds acetyl to 4C compound to make 6C citrate |
| matrix PH | 8 |
| intermembrane space PH | 7 |
| energy output after glycolysis | 28 ATP/glucose |
| healthy cell has in cytosol | [ATP] = 10X [ADP] |
| inputs to pyruvate metabolism | 2x (3C pyruvate) |
| outputs to pyruvate metabolism | 2x (1 CO2 + 2C in acetyl bound to CoA) |
| endosymbiosis hypothesis supported by | 1. mitochondria has 2 membranes (as if engulfed) 2. matrix contains DNA, transcription, translation |
| number of proteins in mitochondria genome | 13 protein coding genes |
| small metabolites enter through the outer membrane of mitochondria thru | porins (proteins form small pores that do not change shape) |
| bigger molecules enter outer membrane of mitochondria thru | transporter proteins |
| inner membrane space | has chaperones and transporters very impermeable |
| lipid transport to mitochondria | phospholipid exchange proteins bind to specific ER lipids, carry in cytosol, deposit into cytosolic leaflet of mitochondria. (there are more steps) |
| lipid found only in mitochondria | cardiolipin (4 long tails) |
| cardolipin important for | Ox. Phosphorylation cytocrome c |
| bad mitochondria can be eliminated by | autophagy |
| peroxisomes | surrounded by a lipid bilyer and has a compartment contains enzymes that produce, use, and eliminate H2O2 |
| peroxisome function | synthesis + degredation of many lipids (ex. Coenzyme A is a peroxisome for fatty acids) |
| peroxisome #'s change by | fission or fusion. |