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Pharamcology Unit 2

Respiratory Drugs

QuestionAnswer
What is albuterol? First line of defense against active asthmatic attack
What is the mechanism of action for pseudoephedrine? Narrows blood vessels in nose
What are the side effects for pseudoephedrine? Abdmoinal pain Palpitations Rash Dizziness N/V Dry mouth
What are the drug interactions for pseudoephedrine? Acetaminophen
What are the indications for pseudoephedrine? Allergic rhinitis Cold Nasal congestion
What are the contraindications for pseudoephedrine? Bronchitis Closed-angle glaucoma MAOI therapy Emphysema
How is pseudoephedrine administered? Orally
What is the name brand of pseudoephedrine? Pseudofed
What is the mechanism of action for phenylephrine? Constricts small blood vessels that supply upper respiratory tract structures
What are the side effects of phenylephrine ? Nervousness Local mucousal dryness Insomina Tremors Palpitations
What are the drug interactions of phenylephrine? Methyldopa MAOI
What are the indications of phenylephrine? Epistaxis Nasal congestion
What are the contraindications of phenylephrine? Narrow-angle glaucoma KDA Diabetes BPH Long-standing asthma
How is phenylephrine administered? Oral Intranasal IV IM SubQ Rectal
What are the systemic effects that Salmeterol has on the body? Angioedema Bronchospasm Headache Tremors Urticarcia
Robitussin and Tessalon Perals are both considered what? Antitussives
What type of drug is hydrocodone? Opioid
What is the mechanism of action for hydrocodone? Suppresses cough reflex by direct action on the cough center in the medulla, also has a drying effect on the mucosa of the respiratory tract
What are the side effects of hydrocodone? Sedation N/V Lightheadedness Constipation
What are the drug interactions of hydrocodone? Naltrexone Samidorphan
What are the indications of hydrocodone? Used in combination with decongestants, antihistamines, and expectorants
What are the contraindications of hydrocodone? KNA Opioid dependency Respiratory depression
What is the brand name of Monelukast? Singulair
What are the drug interactions of monelukast? Dasabuvir Leflunoide Pixantrone Teriflunomide
What is the mechanism of action for oxymetazoline? Constrict small blood vessels that supply the upper respiratory stract structures
What are the side effects of oxymetazoline? Nervousness Local mucosal dryness Insomnia Tremors
What are the drug interactions of oxymetazoline? Methyldopa
WHat are the indications of oxymetazoline? Relief of nasal congestion Rhinitis Cold Sinusitis Hay fever Allergies
What are the contraindications of oxymetazoline? KDA Narrow-angle glaucoma Hypertension Diabetes CVA/TBI
What should you avoid when using oxymetazoline? Caffeine
What is the mechanism of action for acetylcysteine? Increase synthesis of glutathione in the liver
What are the side effects of acetylcysteine? Bronchospasm Drowsiness Fever Clamminess
What are the drug interactions of acetylcysteine? Activated charcoal
What are the indications of acetylcysteine? Mucolytic therapy- thinning of mucus
What kind of drug is guaifenesin? Expectorant
What is the name brand of guaifenesin? Robitussin
What is the mechanism of action of guaifenesin? Loosening and thinning of the respiratory tract secretions that occur in response to GI distress ->thinner mucus, easier to move, used to make cough productive
What are the side effects of guaifenesin? GI upset Dizziness Irritability
What are the drug interactions of guaifenesin? MAOIs Anesthetics CNS depressants ETDH
What are the indications of guaifenesin? Common cold Bronchitis Cough Pertusis Flu Nonproductive cough
What are three bronchodilators? Beta-adrenergic agonists Anticholinergics Albuterol
What is the suffix for anticholinergics? -tropium
What is the mechanism of action for anticholinergics? block acetylcholine to affect the PNS, decreases secretions
What are the side effects of anticholinergics? Dry mouth Palpitations N/V Urine retention
What are the indications of anticholinergics? Prevention of bronchospasm associated with chronic bronchitis or emphysema, NOT for acute s/s
What are the contraindications for anticholingerics? KDA, narrow-angle glaucome
What is the fastest bronchodilator? Albuterol
What is the mechanism of action for albuterol? Activates beta 2 in lungs, dilates bronchi Activates beta 1 in heart, cause rapid HR
What are the side effects for albuterol? Tachycardia Palpitations Tremors Insomina
What are the contraindications of albuterol? Beta blockers NSAIDS
What is the suffix for LRAs? -lukast
What is the mechanism of action for LRAs? Reduce inflammation in reponse to leukotrienes
What are the side effects of LRAs? Headache Abdominal pain Laryngitis
What is the black box warning for LRAs? Serious mood related changes and behaviors
What are the drug interactions for LRAs? NSAIDs TB drugs Warfarin Erythromycia
What are the indications for LRAs? Long term treatment for inflammation- usually given with albuterol and steroids Prevent or lessen allergies and asthma
What are the contraindications for LRAs? Liver disease/toxicity Sleep disorders Kidney disease
How long is the onset for LRAs? 1-2 weeks to reach therapeutic range
What is the suffix for mucolytics? -steine
What is the mechanism of action for mucolytics? Break up and loosen mucus Make productive cough
What are the side effects of mucolytics? N/V severe in large doses Runny nose Stomatitis
What are the indications for mucolytics? Asthma Cold COPD Pneumonia
What are the contraindications for mucolytics? Young children Pregnancy Hypersensitivity
Created by: hannah.cook
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