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Musculoskeletal

BDK

Generic Brand Pharmacological category Common indication Essential knowledge (KSE)
Tizanidine (po) Zanaflex Alpha 2 Agonist Spasticity Drowsiness, hypotension, dizziness , xerostomia, weakness
Hydroxychloroquine (po) Plaquenil Aminoquinolone RA,SLE, malaria Retinal toxicity, rash, diarrhea Other notes: use has been associated with cardiomyopathy, bone marrow suppression, and neuromuscular effects (I.e. myopathy, palsies, and progressive weakness)
Colchicine (po) Colcrys Anti gout agent Gout Key side effect: diarrhea, nausea, vomiting, bone marrow suppression, myopathy (including rhabdomylosis)
Diclofenac (PO) Voltaren NSAID OA, RA, acute pain kse: diarrhea, dyspepsia, abdominal pain, flatulence, nausea BBW: may increase the risk of serious (and potentially fatal) cardiovascular thrombotic events, MI, stroke; may increase the risk for serious gastrointestinal adverse events including ulceratio
Ibuprofen (PO) Motrin, Advil NSAID OA, RA, acute pain kse: diarrhea, dyspepsia, abdominal pain, flatulence, nausea BBW: may increase the risk of serious (and potentially fatal) cardiovascular thrombotic events, MI, stroke; may increase the risk for serious gastrointestinal adverse events including ulceratio
Meloxicam (PO) Mobic NSAID OA, RA, acute pain kse: diarrhea, dyspepsia, abdominal pain, flatulence, nausea BBW: may increase the risk of serious (and potentially fatal) cardiovascular thrombotic events, MI, stroke; may increase the risk for serious gastrointestinal adverse events including ulceratio
Indomethacin (PO) Indocin NSAID OA, RA, acute pain, gout kse: diarrhea, dyspepsia, abdominal pain, flatulence, nausea BBW: may increase the risk of serious (and potentially fatal) cardiovascular thrombotic events, MI, stroke; may increase the risk for serious gastrointestinal adverse events including ulceratio
Naproxen (PO) Naprosyn, Anaprox, Aleve NSAID OA, RA, acute pain, gout kse: diarrhea, dyspepsia, abdominal pain, flatulence, nausea BBW: may increase the risk of serious (and potentially fatal) cardiovascular thrombotic events, MI, stroke; may increase the risk for serious gastrointestinal adverse events including ulceratio
Ketorolac (PO, IV) Toradol NSAID Pain kse: diarrhea, dyspepsia, abdominal pain, flatulence, nausea BBW: may increase the risk of serious (and potentially fatal) cardiovascular thrombotic events, MI, stroke; may increase the risk for serious gastrointestinal adverse events including ulceratio
Celecoxib (PO) Celebrex NSAID, Cox-2 Selective OA, RA, acute pain kse: diarrhea, dyspepsia, abdominal pain, flatulence, nausea BBW: may increase the risk of serious (and potentially fatal) cardiovascular thrombotic events, MI, stroke; may increase the risk for serious gastrointestinal adverse events including ulceratio
Diclofenac (topical) Voltaren Gel NSAID OA pruritus, rash
Cyclobenzaprine (PO) Flexeril Skeletal muscle relaxant Muscle spasm drowsiness, dizziness, xerostomia, fatigue other notes: use may cause prolonged cardiac arrhythmias, and tachycardia; CI within 14 days of MOAI inhibitor therapy
Baclofen (PO) -------- Skeletal muscle relaxant Spasticity Drowsiness
Carisoprodol (PO) Soma Skeletal muscle relaxant Muscle spasm drowsiness other notes: drug abuse potential
Methocarbamol (PO) Robaxin Skeletal muscle relaxant Muscle Spasm Drowsiness
Metaxalone (PO) Skelaxin Skeletal muscle relaxant Muscle spasm drowsiness
Lidocaine (transdermal, IV) Transdermal: Lidoderm, IV: Xylocaine Transdermal: Topical analgesic IV: antiarrhythmic Transdermal: Pain IV: Ventricular arrhythmias (transdermal): dermatitis, erythema, urticaria, skin depigmentation, skin edema IV: Bradycardia Other notes: patch may remain in place for up to 12 hours in any 24-hour period, patch may be cut
Allopurinol (PO) Zyloprim Xanthine oxidase inhibitor Gout Diarrhea, nausea, rash, leukopenia, thrombocytopenia other notes: rare association with severe (and potentially fatal) allopurinol hypersensitivity syndrome (risk highest in certain Asian populations)
Succinylcholine (IV) Anectine Depolarizing neuromuscular blocking agent neuromuscular blockade for intubation or procedures hyperkalemia, myalgia, malignant hyperthermia (rare) BBW: acute rhabdomyolysis and hyperkalemia leading to cardiac arrest and death in pediatric patients with undiagnosed skeletal muscle disease
Created by: sagomez2
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