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DrugNameParts.rsn
Generic Drug Prefixes/Suffixes
| Question | Answer |
|---|---|
| -semide [furosemide*] | Loop/High Ceiling Diuretic [(K)wasting] -prevents reabsorption of Na & Cl in the loop of Henle |
| -thiazide [HCTZ*] | Thiazide Diuretic [(K)wasting] -decreases the reabsorption of NA in the kidney tubule |
| -amide | Carbonic Anhydrase Inhibitor |
| -statin | HMG-CoA Reductase Inhibitor -blocking this enzyme results in less cholesterol biosynthesis (production)- |
| Chole- or Cole- | Bile Acid Resin -bind bile acids resulting in increased excretion of cholesterol in stool- |
| -fibrate or -fibrozil | Fibric Acid Agent -reduces excessive triglyceride (hypertriglyceridemia) & VLDL levels- |
| -nitrate or -nitrite or Nitro- | Organic Nitrate -a vasodilator that relaxes both arterial & venous smooth muscle thereby reducing preload & cardiac output resulting in lowered O2 myocardial demand. Drugs of choice for terminating acute anginal episodes. |
| -olol | Beta-Adrenergic Blocker -reduce cardiac workload by slowing heart rate & reducing contractility (a negative inotropic effect). Drug of choice for treatment of HTN. Also, used in the treatment of HF, dysrhythmias, & chronic angina. |
| -dipine [exceptions: diltiazem, verapamil, & bepridil] | Calcium Channel Blocker -relaxes arterial smooth muscle thereby reducing afterload & lowers O2 myocardial demand. Slows conduction velocity thus reducing workload. Dilates coronary arteries bringing more O2 to myocardium. |
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