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chap 12
| Question | Answer |
|---|---|
| Adverse Gastrointestinal Effect Drug - esophageal ulcer | aspirin, potassium chloride |
| Adverse Gastrointestinal Effect Drug - esophageal reflux | NSAIDs , theophylline |
| Adverse Gastrointestinal Effect Drug - gastritis | NSAIDs |
| Adverse Gastrointestinal Effect Drug - constipation | Aluminum - containing antacids |
| Adverse Gastrointestinal Effect Drug - diarrhea | clindamycin , amoxicillin |
| selected drugs with Decreased elimination in cirrhosis and obstructive jaundice | caffeine , Diazepam , Encainide , Erythromycin , Lidocaine |
| selected drugs with Decreased elimination in cirrhosis and obstructive jaundice | Meperidine, metronidazole , metoprolol , theophylline , verpamil |
| selected drugs with decreased elimination in renal disease | Atenolol , Digoxin , Gentamicin , lithium , |
| selected drugs with decreased elimination in renal disease | piperacilin , ranitidine , vancomycin |
| additive effect- antibiotic effect Treats pneumocystis carinii pneumonia : infection in AIDs patients | trimethoprim + sulfamethoxazole |
| additive effect- for prolongation of hearts OT interval | amiodarone + dofetilide |
| synergistic effect- increased anticoagulation - increased bleeding risk | aspirin + warfarin |
| synergistic effect - increased antibacterial effects of gentamicin | vancomycin + gentamicin |
| potentiation effect - increases duration of amoxicillins antibiotics effect | amoxicillin + clavulanic acid |
| potentiation effect - increased duration of penicillin's antibiotic effect | penicillin + probenecid |
| antidote effect - relief of morphine induced respiratory depression | naloxone + morphine |
| antidote effect - opposition of the anticoagulant effect of warfarin and a return to normal blood clotting time | vitamin k + warfarin |
| antidote effect - in the anticoagulant activity of both drugs | protamine + heparin |
| Flumazenil is a ____ that reverses the sedative effects of diazepam, midazolam, and _____ Flumazonil competes for the same receptors as the benzodiazepine and displaces them | benzodiazepine antagonist , zolpidem |