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Module 12
Section 4: The hematologic system
| Question | Answer |
|---|---|
| What is the hematologic system? | A subset of the cardiovascular system that is made up of blood, blood vessels, and blood-forming tissues such as bone marrow |
| What are the three steps in the formation of a platelet plug? | Platelet activation Platelet aggregation |
| What is the function of fibrin? | Holds the platelet plug in place like a net to form a clot |
| What is thrombin? | A major protein responsible for blood coagulation that works in the clotting cascade and also stimulates platelet activation |
| What is anemia? | A deficiency in the number of red blood cells or hemoglobin, which impairs the blood's ability to carry oxygen to the body's tissues. |
| What is hemophilia? | A hereditary coagulation disorder that results ina decreased ability of the blood to clot normally |
| What is a deep vein thrombosis (DVT)? | A condition characterized by abnormal clotting, usually in leg arteries, in which the leg might appear red, swollen, and painful. A DVT can break apart and lead to other complications, such as a pulmonary embolism |
| What are three causes of iron-deficiency anemia? | Excessive blood loss Low dietary iron intake Malabsorption of iron in the GI tract |
| What is the action of heparin? | Indirectly inhibits thrombin and factor Xa to prevent clotting |
| What is the action of thrombolytic medications? | Converts plasminogen to plasmin to break down clots |