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PTA 211 Exam 1

Multiple Sclerosis

QuestionAnswer
___ is a demyelinating disease of the CNS; characterized by sclerotic plaques disseminated throughout the CNS multiple sclerosis
what does the Charcot's triad consist of? intention tremor scanning speech nystagmus
what can trigger an exacerbation of MS? (4) viral or bacterial infection trauma, pregnancy, stress increased external or internal heat sleep deprivation
the etiology of MS is unknown, but what factors can contribute to it developing? (5) viral infections environmental (possibly smoking, vitamin D deficiency) climate (more common in temperate regions, certain latitudes) genetic certain auto-immune diseases
what auto-immune diseases have a potential link to MS? (4) pernicious anemia thyroid disease type I diabetes IBD
___ occurs when autoantigens attack the body's own myelin, causing myelinization friendly fire
what demographic is MS most commonly found in? Caucasian females, 20-40 years old
diagnostic criteria for MS includes: (3) elevated immunoglobulin in CSF evoked potentials (EP) positive MRI
___ MS is characterized by sudden onset with partial or complete remissions; remains stable for a long time; ~85% of cases relapsing remitting
___ MS is the progression of RRMS to a steady and irreversible decline secondary progressive
___ MS is characterized by progression without remission and severe disability, no distinct attacks; ~10% of cases primary progressive
___ MS is characterized by gradual neurological deterioration from onset with relapses; ~5% of cases progressive relapsing
___ MS is characterized by mild symptoms and little disease progression; ~10-20% of cases benign
___ MS is characterized by rapid progression and significant disability or death within a short period after onset malignant/aggressive
the clinical presentation of MS includes: (4) great variability amongst individuals history of vague functional limitations before definite symptoms can have fast or slow onset psychosocial considerations
signs and symptoms of MS can include: (10) sensory changes (numbness, Lhermitte's sign, dec. proprioception) paresis spasticity pain movement disorders (dysmetria, ataxia, dysdiadokinesia) vestibular dysfunction fatigue visual disturbances cognitive, behavioral, communication disturbances
___ is a hypersensitivity to minor sensory stimuli hyperpathia
people with MS typically feel best at what time of the day? the morning
people with MS usually live ___ years after diagnosis 22-25
a positive ___ sign occurs when flexing the neck results in a 'shock' running down the spine and into the extremities Lhermitte's
the PT evaluation for a patient with MS should include: (12) patient Hx (fatigue) ROM sensation pain muscle tone, strength coordination and balance gait posture respiratory pattern cognitive/behavioral issues visual function functional status
PT treatment for MS can include: (11) sensory impairments, skin care pain spasticity, paresis modalities (cryo, FES) positioning ROM fatigue ataxia (Frenkels) gait functional limitations respiratory care
Created by: saram6450
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