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pharm

Endocrine Quiz questions

QuestionAnswer
Parafollicular cells in the parathyroid secrete: calcitonin
Function of Thyroid: Releases TRH from hypothalamus to stimulate pituitary gland & produce & secrete TSH
Negative Feedback loop: When thyroid hormones reach a certain level in the blood, the secretions of TRH and TSH are slowed down.
Thyroid hormone affects: regulate metabolic rate & critical to growth of the nervous system.
What causes hypothyroidism? Insufficient secretion of TSH or thyroid hormone.
Hypothyroidism in adults is called: myxedema
Signs & symptoms of myxedem? Low body temperture & intolerance to cold, slowed metabolism, slurred speech, bradycardia, weight gain.
Treatment for hypothyroid is: Levothyroxine (Synthroid)
Hyperthyroidism is caused by: Too much thyroid hormone being secreted.
Severe form of hyperthyroidism is: Graves disease
Signs & symptoms of Graves disease: increased body metabolism, tachycardia, weight loss, high body temp, anxiety & exopothalomus (buldging eyes)
Treatment of hyperthyroidism: Thyroidectomy if due to tumorPropylthiouracil (PTU)
Adrenal glands are located?What are the 2 regions of the adrenal glands: Lie on top of kidneyRegions are: Cortex & Medulla
Adrenal Cortex secretes two classes of corticosteroids: Glucocorticoids & Mineralocorticoids
Mineralocorticoids AldosteroneIncreases renal absorption of sodium in exchange for potassium., more sodium and water retention in body.
Function of glucocorticoids: CRF secreted by hypothalamus, ACTH is then released by the pituitary gland, glucocorticoids are released from teh adrenal cortex, when thenglucocorticoid level increases- hormones shut off.
What glucocorticoids do in the body: Long term stress mobilizes the formation of glucose, promotes breakdown & utilization f proteins & lipids, promotes homeostasis of the cardiovascular, nervous & musculoskeltal system.
Signs & symptoms of adrenocortical insufficiency: Hypoglycemia, fatigue, hypotension, GI disturbances.
What are glucocorticoids used to treat? Inflammatory & immune responses such as: allergies, seasonal rhinitis, asthma, hodgkins disease, rheumatoid arthritis
Side effects of Cushings Syndrome: Adrenal atrophy, Osteoporosis, increased risk of infections, delayed woudn healing, peptic ulcer, accumulation of fat around shoulders and neck, mood and personality changes, hyperglycemia.
Common glucocorticoids: Predinisone (Deltasone)Hydrocortisone (Solu-cortef)Methylpredinisolone (Solu-medrol)Dexamethasone (Decadron)Betamethasone (Celestone)
Somatotropin is known as? Growth Hormone
A decrease in Somatotropoin or growth hormone cahses what in children? Dwarfism
Growth Hormone Medications: Somatrem (Protopin) & Somatropin (Humantrope)
Antidiuretic Hormones: Increase water absorption by kidneys conserving water,causes vasopressin & raises blood pressure when secreted in large amounts.
What causes diabetes insipidus? deficiency of ADH (SE polyuria, electrolyte imbalances)
Treatment for Diabetes insipidus? Vasopressin (Pitressin)Desmopressin - used for enuresis (bed wetting) - nasal spray
Created by: kcornwell
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