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Herbal Supplements

Complementary and alternative medicine CAM Includes healthcare systems, practices, and products not considered part of western or allopathic medicine Use continues to increase; most common users are higher lvl educated females ages 50 to 59 (Most common users -women, those with higher level of education, those with health insurance) Increase use means need to be familiar with contraindictions, drug interactions, and side effects Use - greatest is herbal products or dietary supplements
Regulatory history Past dash traditional regulatory agencies did not have regulation over supplements Dietary supplement health and education act of 1994 DSHEA FDA has regulatory authority over supplements National center for complementary and integrative health NCCIH Within the national institute of health NIH Helps oversee CAM in USA
DSHEA - dietary supplement health and education act of 1994 Define dietary supplements as containing a vitamin mineral, herb, or other botanical, amino acid or dietary substance for use to supplement the diet Regulatory authority given to the FDA - Food and Drug administration Not regulated like drugs - prescription or OTC - no clinical trials to establish efficacy/safety Safety established after the fact FDA has to prove risk before pulling from the market Products cannot claim to treat, cure, prevent, or diagnose any disease Products must have FDA disclaimer- "These statements have not been evaluated by the fda. This product is not intended to diagnose, treat, cure, or prevent any disease" May only claim benefit by supporting structure or function "Promotes cell health" "Is heart healthy" Good Manufacturing Practices cGMP - manufacturers have to follow the current Must be labeled as dietary supplement
Misperception-natural equals safe Ma Huang - ephedra Natural source of ephedrine alkaloids - similar to nasal decongestants Combined with other natural source of caffeine - natural diet supplement / energy booster Caused anxiety, heart palpitations, stroke Pulled from the market in 2004
Supplements and safety Herbal supplement - any form of a plant or plant product, including leaves, stems, flowers, roots, and seeds Can see significant drug - herbal interactions 69% of herbal supplement users do not tell their doctors they're using supplements Take accurate medication history Recognize potential dangerous herbal interactions Notify healthcare professional Many drugs are derived from herbs including chemotherapy drugs Europe herbal use - More accepted The European medicines agency - reviews evidence on herbals and recommendations Ema.europa.eu/en/medicines
Echinacea Prevents common colds Beware! Liver toxicity!
Evening primrose Used for - cancer, diabetes, eczema, arthritis, menstrual symptoms Decreases effectiveness of anticonvulsants
Feverfew Fever, headaches, stomach aches, almost like a cure all NSAIDs and warfarin interactions
Garlic For blood pressure and cholesterol Need to eat a lot, r aw best Warfarin - increased risk of bleeding Decreases sequinivir blood levels
Ginger Used for stomach aches, diarrhea, motion sickness, nausea Warfarin interactions
Ginkgo Used for dementia, memory loss Increases blood flow to the brain Interactions - warfarin, trazodone, aspirin - increases the risk of bleeding
Ginseng Improved health, increased stamina, almost like a cure-all Lots of drug interactions - warfarin, insulin, sulfonylureas, metformin, digoxin, phenelzine sulfate
Hawthorne Used for heart disease, digestive problems, kidney problems Interferes with digoxin blood level monitoring
Kava Asthma, uti, fatigue, insomnia, anxiety, menopausal symptoms Can cause liver damage, drowsiness
Saw Palmetto Urinary symptoms from benign prostatic hyperplasia BPH Interacts with - benzodiazepines, cimetadine, terazosin - decreases iron absorption
St John's Wort Used for mental disorders, anxiety, depression Acts like SSRIs Lots of drug interactions, especially with antidepressants
Valerian Sleep disorders Drowsiness - additive
Cranberry UTI prevention and treatment, urinary deodorizer (maybe due to decreasing ammonia) for incontinence Makes urine more acidic for the prevention of UTIs Inconclusive as treatment Not for those at risk for kidney stones - acidity of urine could precipitate calcium
Probiotics Lactobacillus and Bifidobacterium Promotes digestive health Good if on antibiotics to prevent yeast infections
Created by: Adriannld
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