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Anti-inflammatorys
Adverse affects
| Question | Answer |
|---|---|
| Aspirin | gastric effects, respiratory, neurological, bleeding, kidney failure |
| pyrazolone derivatives | GI |
| proprionic acid derivatives (ibuprofen, ketoprofen, carprofen, naproxen) | GI ulceration, vomiting, anorexia, carprofen has potential for hepatotoxicity in dogs |
| deracoxib | vomiting, diarrhea, elevated kidney/liver values |
| firocoxib | vomiting (if possible) and anorexia |
| robenacoxib | GI (vomiting, diarrhea, ulceration) |
| meloxicam | anorexia, vomiting, diarrhea, lethargy |
| flunixin meglumine | GI signs and ulceration, perivascular necrosis |
| gapriprant | vomiting, diarrhea, inappetance |
| diclofenac sodium | minimal although gloves worn for application |
| dimethyl sulfoxide | local irritation (wear gloves when applying) |
| acetaminophen | k9: hepatotoxicity. cats: extremley toxic |
| ketamine | minimal at low doses |
| amantadine | minimal |
| hyaluronic acid | local reactions, minimal |
| PSGAGs | local reaction, minimal |
| glucosamine and chondroitin sulfate | minimal |
| antihistamines | drowsiness, dry MM, CNS stimulation(high doses), |
| cyclosporine | neoplasia, decreased response to vaccination |
| oclacitinib | vomiting, diarrhea, increased risk of infection, neoplasia |
| piroxicam | GI ulceration, nephrotoxicity, narrow therapeutic index, long half life, possibly teratogenic |