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Endocrine 2
FSOP 2022-2023 Drugs
| Brand | Generic | Category | Indication | Side Effects | Boxed Warning |
|---|---|---|---|---|---|
| drospirenone and ethinyl estradiol (PO) | Yasmin, Yaz | Contraceptive | Contraception, acne | changes in menstrual flow, breast tenderness, thrombolytic disorders | increased risk of cardiovascular events in women >35 years old who smoke |
| levonorgestrel and ethinyl estradiol (PO | Lutera, Levora, Seasonique | Contraceptive | Contraception, acne | changes in menstrual flow, breast tenderness, thromboembolic disorders | increased risk of cardiovascular events in women >35 years old who smoke |
| norethindrone and ethinyl estradiol (PO) | Junel, Loestrin, Microgestin | Contraceptive | Contraception, acne | changes in menstrual flow, breast tenderness, thromboembolic disorders | increased risk of cardiovascular events in women >35 years old who smoke |
| norethindrone, ethinyl estradiol, and ferrous fumarate (PO) | Lo Loestrin Fe, Microgestin Fe | Contraceptive | Contraception, acne | changes in menstrual flow, breast tenderness, thromboembolic disorders, | increased risk of cardiovascular events in women >35 years old who smoke |
| norgestimate and ethinyl estradiol (PO) | Ortho Tri-Cyclen Lo, Tri-Sprintec, Sprintec | Contraceptive | Contraception, acne | changes in menstrual flow, breast tenderness, thromboembolic disorders | increased risk of cardiovascular events in women >35 years old who smoke |
| norgestrel and ethinyl estradiol (PO) | Crysell-28, Low-Ogestrel | Contraceptive | Contraception, acne | changes in menstrual flow, breast tenderness, thromboembolic disorders | increased risk of cardiovascular events in women >35 years old who smoke |
| estrogens, conjugated (equine) (PO, topical) | Premarin | Estrogen derivative | Vasomotor symptoms associated with menopause, vaginal atrophy associated with menopause | irritation at application site (transdermal patch only), abdominal pain, breast tenderness, thromboembolic disorders | increased risk of breast cancer; should not be used for dementia prevention; increased risk of endometrial cancer |
| estradiol (transdermal, PO) | Transdermal: Vivelle Dot, PO: Estrace | Estrogen derivative | Vasomotor symptoms associated with menopause, vaginal atrophy associated with menopause | irritation at application site (transdermal patch only), abdominal pain, breast tenderness, thromboembolic disorders | increased risk of breast cancer; should not be used for dementia prevention; increased risk of endometrial cancer |
| medroxyprogesterone (PO) | Provera | Progestin | Abnormal uterine bleeding, secondary amenorrhea | acne, abnormal menstrual bleeding | estrogen or progesterone-dependent tumors, undiagnosed abnormal genital bleeding, hepatic impairment |