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TCA
Antidepressants - Amitriptyline
Term | Definition |
---|---|
Action | - Inhibit reuptake of norepinephrine or serotonin in the brain |
Use | - Depression - Bipolar - OCD |
ADRs | - ***DRY MOUTH - Incompatible with MAOI - Constipation - Photosensitivity - Involuntary movements - Tachycardia - Neuro issue (life-threatening) |
Contraindications | - Glaucoma - MI - Children - Urinary retention - Cardiac disease - Renal / hepatic impairment - Seizure history - Suicidal |
Interactions | - Sedatives --> respiratory depression - Cimetidine --> dry mouth - MAOI --> increased risk for high BP, high fever, severe convulsions - Adrenergic --> increased risk for arrhythmias + high BP |
Medication Administration | - IM 20-30mg 4 times a day - PO 300mg MAX |