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SSRIs
Antidepressant - Zoloft
| Term | Definition |
|---|---|
| Action | - Inhibit CNS uptake of serotonin - Increase in serotonin levels is thought to act as stimulant to reverse depression |
| Use | - Depression - Anxiety - Premenstrual dysphoric disorder - OCD - Bulimia nervosa |
| ADRs | - **Serotonin syndrome (too much serotonin) - Dilated pupils - Irregular heartbeat - *Sexual issues - Muscle spasms |
| Contraindications | - Grapefruit juice |
| Interactions | - Other antidepressants - Cimetidine (supposed to relive gastric upset) can cause dry mouth - NSAID --> GI bleed - Lithium (for bipolar) --> toxicity |
| Medication Administration | 50-200mg daily |
| Client Education | - Takes weeks to months to work - Do not stop drug abruptly - Watch behavioral change - Careful in sun - Mood log |