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CNS Stimulants

Amphetamines, Analeptics & Anorexiants

TermDefinition
Central Nervous System Brain & spinal cord →the way the body processes all of the incoming information - brain controls most of the functions (including awareness, senses, movement, speech)
Peripheral Nervous System - Nerves that branch out from brain and spinal cord who serve as a communication network between CNS and PNS - Divided into Somatic (skin and muscles/conscious activities) and automatics system (unconscious response such as stomach)
CNS Stimulant: Amphetamines - Stimulate the release of norepinephrine in the sympathetic nerve pathway - They are often use to ADHD - Model Drug - Methylphenidate or Ritalin - Drugs in this class usually end in the suffix “ate” or “mine”
CNS Stimulant: Analeptics - Thought to bind dopamine and keep it from being absorbed - Used to treat Narcolepsy - Model Drug - Modafinil/Provigil - Drugs in this class often end in suffix “nil”
CNS Stimulant: Anorexiants - Similar to amphetamines, suppress appetite through hypothalamus, cause euphoria - Used to treat obesity - Model Drug - Phentermine/Adipex-P
ADRs Anxious, hyperactive, tachycardia
Contraindications / Interactions - Interacts with anesthetics, oral contraceptives, and bronchodilator - Contraindicated with convulsive disorders, COPD, cardiac arrhythmias, hypertension, do not give with antidepressants or within 14 days, glaucoma, pregnancy category X
Should a COPD patient use CNS Stimulants? NO (causes respiratory depression)
What should you always check for CNS Stimulant patients? Respiration Rate, Heart Rate, and Rhythm
Is caffeine good to combine with CNS Stimulants No
Who are anorexiants intended for? BMI over 30 (27 if a comorbidity occurs)
Created by: alowe26
Popular Pharmacology sets

 

 



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