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NSAIDS

Ibuprofen (advil, motrin, caldolor)

QuestionAnswer
What are NSAIDS? Non-steriodal anti-inflammatories
NSAIDS are composed of... Analgesic (pain relief), anti-inflammatory, and antipyretic (fever reducer) properties
Expected Pharmacological Action Block enzymes COX-1 and COX-2 from prostaglandin synthesis (controls process of inflammation).
Therapeutic Use Mild-moderate pain Dysmenorrhea (pain during period) Fever Reduction Arthritis
Complications GI bleeding Ulcers Renal failure Stomach pain Bloody or coffee ground vomit Bloody or Black stool
COX 1 enzyme that maintains stomach lining
COX 2 enzyme that triggers pain and inflammation
Contraindications Allergy to NSAIDs or Aspirin (cross rxn) Third trimester of pregnancy/lactation Post-Op pain in CABG patients osteoarthritis - meloxicam
Precautions Pregnancy category B Older adults Bleeding disorders Renal Disease CV Disease Hepatic impairment
Interactions Anticoagulants- Prevent blood clots - increased risk of bleeding Lithium, Cyclosporin, Hydantoins due to toxicity Diuretics lose effectiveness (Kidney's overwhelmed) Long-term acetametophin - renal impairment
Medication administration OTC 400mg every 4-6 hours PRESCRIBED - 800mg Max- 3.2g
Nursing Interventions / Client Education Take with food, milk, or anti-acids Vulnerable to GI bleeding Visual disturbances possible
Evaluation Therapeutic use achieved, discomfort reduced ADRs reported, patient understands what to look for
Created by: Mplaster
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