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merrill
merrill grp3
| Question | Answer |
|---|---|
| Glucophage Preg - B biguanides | metformin types 2 DM CI: metabolic acidosis, renal dysfunction, IV radiography w/iodinated contrast, HF ADR: **lactic adcidosis, *abd bloating, *NVD, *lowers BG-blood glucose, metalic taste, lower vit. B12 |
| Mevalotin/Pravachol Preg - X "statin" - HMG-CoA reducase inhibitor | pravastatin cholesterol, primary/secondary prevention of CV disease CI: liver disease, pregnancy/lactation ADR: **Rhabdomyolysis, myalgia, HA, abd cramps, "bowels" dyspepsia, flatulence, ^LFTs, nausea, rash |
| Biaxin & XL - extended release Preg - C macrolides | clarithromycin:respiratory tractinfections, pharyngitis/tonsillitis, CAP, OM/otitis media, skin infections, MAC infections, CI:pregnancy/last choice, macrolides, or ketolides, using pimozide or ergot derivatives, ADR: **pseudomembranous colitis, infectio |
| Avastin Preg - C monocolonal antibodies | bevacizumab metastic colorectal CA,nonsmall lung CA, nonchemo HER2 CI:1st 28 days after surgey, hemoptysis/other bleeding ADR:**Thromboembolic events, **GI perferation, **Bleeding, impaired healing, wound dehiscence-surgical, infusion reactions, |
| Avapro Preg - C 1st trimester, D 2nd & 3rd trimester angiotensin 2 receptor antagonists | irbesartan HTN, diabetic nephropathy in pts w/type 2 DM, CI: pregnancy/lactation ADR:**Angioedema, ^HR, lower BP, ^K+, NVD, dizzy, fatigue, ^SCr-serum creatinine, dyspepia |
| Zyrtec Preg - B antihistamine | cetirizine seasonal/perinial rhinitis, chronic uriticara-hives, CI:allergic cetirizine, or hydroxyzine, lactation ADR:dizzy, HA, drowsy, fatigue, insomnia, pharyngitis, dry mouth, NVD |
| Proscar Preg - X androgen inhibitors | Finasteride BPH-benign prostatic hyperplasia, male pattern baldness (can use w/doxazosin) CI: women, Peds ADR: impotency, lower libido |
| Epogen Preg - C colony stimulating factors | epoetin alfa Anemia renal failure, Chemo induced, HIV(Zidovudine therapy)reduction of transfusion after surgey, CI:allergic-albumin, or mammalian cell products, ADR:**Seizures, **Arrythmias, **HF, **MI, **stroke,**Thrombic events, **mortality, |
| Aricept Preg - C cholinergics | donepezil dementia related to Alzheimer's disease (AD), CI:lactation ADR: *HA, *NVD, abnormal dreams, depression, insomnia, 6BP, lower HR, dizzy, fatigue, drowsy, ecchymos - bruise w/underlying bleeding, arthritis, muscle cramps, anorexia, lower weight |
| Ambien Preg - C sedative/hypnotic | zolpidem insomnia CI:sleep apnea, previous h/o abuse ADR: abnormal thinking, anxiety, depression, behavior changes, day/drowsy, hallucinations, sleep driving, ^BP, HA, NVD, physical/psychological dependency |
| Lexapro Preg - C SSRI selective seritonin reuptake inhibitor | Escitalopram depression, GAD CI:current MAOI or pimozide therapy, suicidal, ADR: suicidal, *HA, *insomina, *dry mouth, ND, ^appetite, ED, ejaculatory delay, lower libido, ^sweating |
| Zocor Preg - X "statin" HMG-CoA | simvastatin cholesterol, primary & 2nd prevention CV disease CI:liver disease, pregnancy/lactation, ADR: **Rhabdomyolysis, myalgia, abd cramps, "bowels" dyspepsia, flatulence, nausea, rash |
| Actos Preg - C antidiabetics | pioglitazone NIDDM, CI:acute liver disease, or ^ALT-alanine aminotransferase, IDDM, moderate/sever HF, hepatic imparement, ADRedema, hepatitis, anemia, fractures (women)(arm, hand, foot)^LFTs |