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Infect. Diseases 4
Infectious Diseases 4
| Generic Name | Brand Name | Pharmacologic Category | Common Indications | Key Side Effects/Other Notes | US Boxed Warning |
|---|---|---|---|---|---|
| terbinafine (PO, topical *) | Lamisil | Allylamine antifungal | Onychomycosis | Key Side Effects: nausea, abdominal pain, diarrhea, elevated hepatic transaminases, headache | |
| acyclovir (PO, IV) | Zovirax | Antiviral | Herpes simplex virus | Key Side Effects: nausea, increased hepatic transaminases, crystalluria Other Notes: vesicant | |
| valacyclovir (PO) | Valtrex | Antiviral | Herpes simplex virus | Key Side Effects: nausea, increased hepatic transaminases | |
| fluconazole (PO, IV) | Diflucan | Azole antifungal | Vulvovaginal candidiasis, oropharyngeal candidiasis | Key Side Effects: nausea, abdominal pain, diarrhea, QTc prolongation, elevated hepatic transaminases | |
| ketoconazole (PO, topical *) | Nizoral | Azole antifungal | Fungal infections | Key Side Effects: nausea, abdominal pain, diarrhea, QTc prolongation, increased hepatic transaminases | US Boxed Warning: serious hepatotoxicity, including cases with a fatal outcome or requiring liver transplantation, have occurred; may cause QTc prolongation and drug interactions leading to QTc prolongation |
| oseltamivir (PO) | Tamiflu | Neuraminidase inhibitor antiviral | Influenza | Key Side Effects: nausea, vomiting, neuropsychiatric events (i.e., confusion, delirium, hallucinations) in pediatric patients (rare) | |
| nystatin (PO) | ------- | Polyene antifungal | Oropharyngeal candidiasis | Key Side Effects: no major side effects | |
| nystatin (topical) | Nystop | Polyene antifungal | Cutaneous and mucocutaneous fungal infections | Key Side Effects: burning, itching Other Notes: only use oral solutions for thrush | |
| micafungin (IV) | Mycamine | Echinocandin antifungal | Invasive candidiasis | Key Side Effects: no major side effects | |
| betamethasone and clotrimazole (topical) | Lotrisone | Glucocorticoid and azole antifungal | Cutaneous fungal infections | Key Side Effects: burning, itching, dryness, skin atrophy Other Notes: do not use for diaper dermatitis; adrenal suppression with long-term use over large areas of skin |