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Antituberculosis Med

Stack #35751

QuestionAnswer
Tb symptoms weight loss, malaise, fever, cough that is worse in the AM
Tuberculosis caused by Mycobacterium tuberculosis
Transmission droplets from infected person in the air by cough or sneeze
Organs affected by Tb CNS (Meninges), bones and joints, skin, eyes, kidney, ureter, bladder
Treatment for Tb 4 drug regimen
Drugs for Tb Isoniazid (INH), Rifampin (Rifadin), Ethambutol (Myambutol), Pyrazinamide
Isoniazid Brand Name INH
Rifampin Brand Name Rifadin
Ethambutol Brand Name Myambutol
Isoniazid M.O.A inhibits the production of mycolic acid
Isoniazid M.O.A inhibits production of mycolic acid
Isoniazid side effects fever, rash, CNS disturbances, peripheral neuritis - can be prevented by taking vitamin B6, hepatitis - more common in those over 35 and who drink alcohol
Rifampin M.O.A inhibits bacterial enzyme required for RNA synthesis
Rifampin side effects GI disturbances, rash, headache, hepatoxicity, flu like syndromewhen not taken regularly
Ethambutal M.O.A believed to be inhibition of mycolic acid in cell wall
Pyrazinmide M.O.A M.O.A is not well understood
Ehtambutal side effects fever, rash, GI disturbances, blurred vision
Pyrazinamide side effects most serious: hepatoxicity, hyperurecemia, gout
Created by: TBess
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