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Anti-Fungals
Stack #35745
| Question | Answer |
|---|---|
| Fungi | yeasts or molds - plant like microoganisms found in soil, air and contaminated foods |
| Mycotic infection | fungal infection that cause itching, blisters, broken skin between toes, scaling patches on skin |
| Anti-fungals spectrum | selective spectrum of activity |
| Fungicidal | kills fungi, usually systemic acting drugs |
| Fungistatic | prevents fungal growth |
| Amphortericin B - M.O.A | binds to fungal membrane producing a change in the cell's permeability causing nutrients & ions to leak out leading to cell death |
| Griseofulvin - M.O.A | binds to infected keratinized tissue preventing the fungus from invading the healthy tissue |
| 3 types of human fungal infections | Systemic, Dermatophytic, Candidiasis |
| Drug of Choice for systemic infections | Amphortericin B |
| Drug of Choice for Dermatophytic infections | Griseofulvin |
| Amphotericin B Brand Name | Fungizone |
| Griseofulvin Brand Name | (blank) |
| Drugs used for Candida Infections | amphotericin B, ketoconazole (Nizoral), miconazole (Micatin, Monistat), clotrimazole (Gyne-Lotrimin and Lotrimin AD), nystatin (Mycostatin) |