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Cell Reg Chart

QuestionAnswer
Alkylating agents- Drugs Cyclophosphamide, cisplatin, carmustine
Alkylating agents- Action Blocks synthesis of DNA and RNA
Alkylating agents- Side Effects N & V, diarrhea, alopecia, hemorrhagic cystitis
Alkylating agents- Nursing Interventions Within days # of erythrocytes, leukocytes & platelets declines.
Antimetabolites- Drugs Methotrexate, floxuridine, fluorouracil
Antimetabolites- Action Interfere w/nutrient or nucleic acid metabolism in tumor cells
Antimetabolites- Side Effects N & V
Antimetabolites- Nursing Interventions Leucovorin used adjunct to “rescue” normal cells, protect against bone marrow damage Alkalinize urine to protect kidneys from methotrexate toxicity
Antitumor antibiotics- Drugs Doxorubicin, bleomycin, dactinomycin, daunorubicin
Antitumor antibiotics- Action Kill cancer cells
Antitumor antibiotics- Side Effects Doxorubicin- Cardiotoxicity- minutes, months or years later Bleomycin- pulmonary fibrosis
Antitumor antibiotics- Nursing Interventions Bone marrow suppression- dose limiting
Natural products/plant alkaloids- Drugs Vincristine, vinblastine, paclitaxel
Natural products/plant alkaloids- Action Inhibit cell division
Natural products/plant alkaloids- Side Effects Peripheral neuropathy, parathesia
Natural products/plant alkaloids- Nursing Interventions Bone marrow suppression- dose limiting
Hormones/hormone antagonists- Drugs Dexamethasone, testosterone, medroxyprogesterone, tamoxifen
Hormones/hormone antagonists- Action Slows growth of hormone dependent tumors
Biologic Response Modifiers & Monoclonal Antiboties- Drugs Interferons, interleukins, cytokines
Biologic Response Modifiers & Monoclonal Antiboties- Action Enhance body’s defenses to destroy cancer cells
Created by: Justinkge
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