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Merrill drug, class
Merrill drug, class, use
| Question | Answer |
|---|---|
| Statin | cholesterol,prevention of CV disease Lipitor - atrovastatin Zocor - simvastatin, Mevalotin/Pravachol - pravastatin, Crestor - rosuvastain, Lescol - fluvastatin, Vytorin - ezetimibe + simvastatin Pravachol - pravastain |
| Monocolonal antibodies | matastic breast tumors with overexpression of human EGRF2 (HER2, metastic colorectal CA, Herceptin - tratuzumab Avastin - bevacizumab - colorectal/lung CA, |
| Angiotensin 2 receptor antagonist | HTN, diabetic nephopathy due to DM type 2 Stroke prevention inpatients with HTN & LVH Czaar - losartan, Avapro - irbesartan, Atacand - candesartan, Benicar - olmesartan |
| Antithrombic, Heparin (low molecular weight) | prevention of DVT & PE - pulmonary embolism, in surgical & medical patients, Treatment of DVT(with Warfarin),& ACS - acute coronary syndrome (UA/NSTEMI or STEMI)- unstable angina/ST-segment elevation myocardial infarction Lovenox - enoxaparin |
| Antilipidemic H2O soluble | cholesterol, prevent Pellagra - niacin defifiency, combat clogged arteries, heart disease Niaspan - niacin (not in book) |
| Leukotriene receptor antagonist | asthma, allergic rhinitis, exercise induced bronchconstriction Singular - montelukast |
| bisphosphonates | osteoporosis/post menopausal, corticosteroid induced osteoporosis, patients receiving > 7.5mg predisone /d with BMD, Paget's disease Fosamax - alendronate, Actonel - risedronate, Boniva - ibandronate, Zometa - zoledronic acid |
| thiazolidnediones | NIDDM - noninsulin dependent diabetes mellitus Avandia - rosglitazone |
| Colony-stimulating Factors | anemia in chronic renal failure, secondary to HIV, Chemotherapy induced anemiain nonmyeloid malignancies, reduction of transfusions after surgery Procrit - erythropoietin - epoetin alfa Epogen - epoetin alfa |
| dMARD anti TNF tumor necrosis factor | RA, juvenile idiopathic arthritis, psoratic arthritis, ankylosing spondylitis, plaque psoriasis Enbrel - etanercept |
| SNRI - seritonin norepinephrin reuptake inhibitor | depression, anxiety, panic disorder, GAD, SAD Effexor - venlafaxine |
| Antipsychotic | Psychosis, schizophrenia, bipolar mania, irritability with autism, Risperdal - resperidone Seroquel - quetiapine - bipolar depression |
| ARB angiotensin 2 Receptor Blocker | HTN Diovan - valsartan |
| CCB calcium channel blocker | chronic stable angina documented CAD without HF Norvasc - amlodipine Amlodin - not sold in USA, Adalat - nifedipine - HTN / pulmonary HTN |
| dMARD monocolonal antibodies | Crohn's, RA, psoratic arthritis, ankylosing spondylitis, ucerative coloitis, plaque psoriasis, Remicade - infleximab Humira - adalimumab, |
| PPI proton pump inhibitor | GI disorders, GERD, esophagitis, hypersecretory-Zollinger-Ellison syndrome, H. pylori eradication in duodenal ulcer disease with (-cillin & -mycin) Nexium - esomeprazole, Protonix - pantoprazole, Prevacid - lansoprazole, Prilosec - omeprazole |
| Antiplatelet agent | thrombic events, atherosclerotic events, (MI,stroke, vascular death, or at risk of)established PAD, ACS, Plavix - clopidogrel |
| Corticosteroids & B2 agonist | asthma, Adivair - fluticasonet + salmeterol, |
| Atypical antipsychotics | schizophrenia, bipolar /agitation, Abilify - aripiprazole, |
| beta-blockers | HTN, angina/MI, stable HF Toprol - metoprolol, Coreg - carvedilol, |
| cyclopyrrolones | Insomnia Lunesta - eszopiclone, |
| 5-HT antagonists | nausea/vomiting from chemo/radiation therapies Zofran - ondansetron, |
| antidiabetics | NIDDM - noninsulin dependent diabetes mellitus Actos - pioglitazone |
| SSRI - selective seritonin reuptake inhibitor | depression, GAD Lexapro - escitalopram, Zoloft - sertaline, Paxol - paroxetine , OCD, PSTD, PMDD |
| Seditive/hypnotic | insomnia Ambien - zolpidem |
| cholinergics | demintia, AD - alzheimer's disease Aricept - donepezil |
| androgen inhibitors | BPH -benign prostatic hyperplasia, male pattern baldness, Proscar - finasteride |
| antihistamines | seasonal/perinial rhinitis, chronic uriticara - hives,rash, Zyrtec - cetirizine, Loratadine - Claritan, |
| biguanides | type 2 DM Glucophage & XR - metformin |
| macrolides | respiratory infections, infections - skin, pharynx, tonsillitis, otits media, CAP, MAC Biaxin - clarithromycin Zithromax - azithromycin |
| corticosteriods | Asthma, topical inflammation, Flonas - fluticasone, Pulmicort - budesonide, Flovent - fluticasone |
| purine analogue | genital herpes, shingles, herpes libialis - (cold sore), Valtrex - valacyclovir |
| neuramidase inhibitors | treatment/prevention influenza, Tamiflu - oseltamivir, |
| anticonvusants | seizures, Lennox-Gastaut symdrome, Topamax - topiramate, Lamictal - lamotrigine, Depakote - valproic acid + derivatives levetiracetam - keppra |
| COX 2 inhibitor cyclooxygenase 2 inhibitor (NSAID) | osteoarthritis, RA, colorectal polyps Celebrex - celecoxib |
| pneumocoocal 7-Valent Vaccine | pneumococcal 7-Valent, vaccine Prevar - pneumococcal7-Valent conjugated vaccine |
| FQs - fluoroquinolone | respiratory infectins, gonorrhea, typhoid fever, Cipro - ciprofloxacin Levaquin - levofloxacin/infections & ocular, Cravit - levofloxacin, Avelox - moxifloxacin |
| sulfonylureas | type 2 DM Amaryl - glimepiride |
| cholesterol absorption inhibitors | cholesterol Zetia - ezetimibe |
| fibric acid derivatives | cholesterol TriCor - fenofibrate |
| interferons | MS Avonex - interferon Pegasys - peginterferon - HEP B&C, |
| dopamine reuptake inhibitors | depression, SAD prevention, stop smoking, Wellbutrin - buPROPion |
| Anticolergenics | bronchospasm due to COPD Spiriva - tiotropium, Combivent - ipratropium |
| NSAID | RA, OA, ankylosingspondylitis, dysmenorrhea Voltaren - diclofenac, Mobic - meloxicam, |
| 5-HT agonist | acute migraines Imitrex - sumatriptan, |
| 5.2 andrenolytics ? beta blocker | HTN, angina, MI, Concor - bisoprolol, |
| antifungal | fungal infections, candidiasis - systemic/BMT, UTIs, oropharyngeal, esophogeal, cryptococcal meningitis, Difulcan - fluconazole, Lamisil - terbinafine - tinea ... |
| SSR agonist | chronic IBS, chronic constipation, <55 yrs, NOT on Market, Zelnorm/Zelmac - tegaserod |
| calcium channel blocker + ACE inhibitor CCB + ACE inhibitor | HTN, Lotrel - amlodipine + benazepril hydrochloride |
| SSNRI selective serotonin/norepinephrine reuptake inhibitor | depression, diabetic peripheral neuropathy, GAD, Cymbalta - duloxetine |
| pancreatics | DM, Humalog - insulin lispro, Humlin -NPH insulin, hyperglycemia, DM, Lantus - insulin-glargine, |
| adrenergics | bronchospasm/airway disease, Xopenex - levalbuterol, |
| ACEI angiotensin-converting enzyme inhibitor, | HTN, post MI, HF, CV death, Delix - ramipril, Vasotec - enalapril, Altace - ramipril, |
| opoid agonist | Pain moderate/severe Duragesic - fentanyl, |
| NRTI nucleoside reverse transcriptase inhibitor, | HIV Truvada - emtricitabine + telnofovir, |
| Formeterol - long acting beta 2 agonist + budesonide - coticosteroid | bronchodilator, asthma, COPD, emphysema, Symbicort - budesonide + formoterol, |
| Incretrin mimetic agents | type 2 DM, sulfonylurea, thiazoidinedione, Byetta - exenatide, |
| peripherally acting antiadrenergics | BPH, Cardura - doxazosin (HTN, immediate release only) |
| H2 antagonist | duadenal & gastric ulcers, GERD, zantac - ranitidine, |
| GABA analogues nonopoidalanalgesic | diabetic peripheral neuropathy, postherpetic neuralgia, firbromyalgia, partial on-set seizures, Lyrica - pregabalin, |
| selective estrogen receptor modulators | prevent/treat osteoporosis, lower breast CA risk in menopausal women, Evista - raloxifene |
| estrogens | mod-severe vasomotor symptoms, estrogen deficiency, prostatic CA, post menopausal osteoporosis, female hypogondism, Premarin - conjugated estrogens |
| enzyme inhibitor | non small cell lung CA, unresectable pancreatic CA, Tarceva - erlotinib |
| penicillan/antibiotic | respiratory infection, OM, skin/skin infection, sinus infection, UT infection, Augmentin - amoxicillin/clavulanate, Zoysin - piperacillan/tazocatam - extended spectrum |
| protease inhibitor | HIV Kaletra - lopinavir/ritonavir Reyataz - atazanavir - with other meds |
| antimuscarinic | over active bladder, incontinence, Detrol - tolterodine |
| alpha - adrenergic blocker | BPH difficulty urinating, Flomax - tamsulosin |
| thyroid preparations | thyroid supplement synthroid - lovothyroxine |
| clotting factor 7A haemostastic | hemophilia A or B Novo Seven - coagulation factor 7A |
| CNS stimulant (central nervous system | ADHD, nacrcolepsy Concerta - methylphenidate, Adderall - amphetamine mixture - dextroamphetamine |
| neurotoxin skeletal muscle relaxant | cervical distonia, upper limb spasicity, severe hyperhydrosis, eye muscle conditions, wrinkles, Botox - onabotulinum toxin |
| neucloside analogues reverse transcriptase inhibitors | HIV, Combivir - lamivudine / zidovudine |
| diphtheria, tetanus, pertusis, Hep B & polio Vaccine | Pediarix - vaccine |
| 3rd generation cephalosporins | respiratory infections OM, Omnicef - cefcinir |
| echinocandins | fungus/mold infection, invasive Asperigillosis, Cancidas - caspofungin |
| anti immunoglobulin monocolonal antibody / antiasthma | asthma, xolair - omalizumab |
| cholesterol lowering agent | cholesterol, Vytorin - ezetimibe/simvastatin |
| Aromatase inhibitor | breast cancer, ovarian cancer, Anastrazole - arimidex |
| Hep B vaccine | Engerix B |
Created by:
Nutty
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