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Penicillins 🌻
| Question | Answer |
|---|---|
| Inhibit cell wall synthesis of bacteria | Beta lactams , Vancomycin , Teicoplanin |
| 1.Beta lactams | Penicillins , Cephalosporins , Carbepenums , Monobactum , Beta lactamase inhibitor |
| Classification of penicillin | |
| Narrow spectrum | Benzyl penicillin (G) Phenoxymethyl penicillin (V) Anti staphylococcal penicillins |
| Broad spectrum | Ampicillin , amoxicillin , bacampicillin Mecillinam Antipseudomonal Beta lactamase inhibitor combinations |
| Adverse effects | Hypersensitivity reaction , Anaphylactic shock, Allergic reactions, |
| Non allergic adverse reactions | Diarrhea , Neutropenia, Rarely anemia,thrombocytopaenia ,intestinal nephritis, Accumulations of na k, Encephalopathy in high doses, |
| 2. Vancomycin | Glycopeptide or peptolide |
| Effective against | Most strains of clostridia, All strains of staphylococcus aureus, |
| Route | Iv , orally poorly absorbed |
| Adverse effects | Ototoxicity, Nephrotoxicity, Allergic reactions, Phelbitis on rapid infusion, |
| Uses | Prophylaxis, Multi resistant stphylococci, |
| 3. Teicoplanin | Simillar to vancomycin |
| Route | Iv, IM |
| Adverse reactions | Akin rash, hypersensitivity , blood disorders , rarely otoroxicity |
| Uses | Endocarditis, Dialysis associated peritonitis, Serious infections due to staphylococcus aureus |