Save
Busy. Please wait.
Log in with Clever
or
show password
Forgot Password?
Don't have an account?  Sign up 
Sign up using Clever
or
Username is available taken
show password


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account. Your email address is only used to allow you to reset your password. See our Privacy Policy and Terms of Service.

Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.
focusNode
Didn't know it?
click below
 
Knew it?
click below
Don't Know
Remaining cards (0)
Know
0:00
edit
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how

Local Anesthetics

Pharmacology

Local Anesthetics
Structure tertiary amine attached to aromatic ring with either an ester or amide linkage; basic; termed aminoesters or aminoamides
Mechanism of Action when electrostatic forces cause sodium channels to open, the local anesthetic, in its charged form, binds to its channel receptor and blocks the channel; local anesthetics can only enter through the lipid membrane in its uncharged form
Potency potencies are compared through their minimal blocking concentration, or Cm; Cm is the drug concentration that just halts impulse traffic over an in vitro 10 mm length of nerve
Duration of Action associated with drug's affinity for plasma alpha-1 acid glycoprotein
Concept of Differential Block A, B, and C nerve fibers; small B and unmyelinated C fibers require a lesser concentration of local anesthetic to produce conduction block than do the thicker myelinated A fibers
Organization of Nerves into Bundles nervve fibers are grouped into bundles; motor fibers are usually in the periphery, while sensory fibers are in the core; motor block will often be seen before sensory block
Routes of Metabolism aminoesterases are metabolized by cholinesterases in the plasma and liver; aminoamides are metabolized by the liver
CNS Effects excitatory; lightheadedness, dizziness, muscle twitching, seizures
Cardiovascular Effects depresses myocardial conduction
Bupivacaine 70x more potent than lidocaine in depressing myocardial conduction
Local Anesthetics Procaine, Lidocaine, Mepivacaine, Tetracaine, Bupivacaine
Created by: DrCutiepie
Popular Pharmacology sets

 

 



Voices

Use these flashcards to help memorize information. Look at the large card and try to recall what is on the other side. Then click the card to flip it. If you knew the answer, click the green Know box. Otherwise, click the red Don't know box.

When you've placed seven or more cards in the Don't know box, click "retry" to try those cards again.

If you've accidentally put the card in the wrong box, just click on the card to take it out of the box.

You can also use your keyboard to move the cards as follows:

If you are logged in to your account, this website will remember which cards you know and don't know so that they are in the same box the next time you log in.

When you need a break, try one of the other activities listed below the flashcards like Matching, Snowman, or Hungry Bug. Although it may feel like you're playing a game, your brain is still making more connections with the information to help you out.

To see how well you know the information, try the Quiz or Test activity.

Pass complete!
"Know" box contains:
Time elapsed:
Retries:
restart all cards