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Drug list

Chap. 19 Gastrointestinal System Medications

BrandGenericMOAIFU Classification
Milk of Magnesia magnesium hydroxide Neutralize acidic stomach contents Peptic ulcers, GERD, acid indigestion Antacids
TUMS calcium carbonate Neutralize acidic stomach contents Peptic ulcers, GERD, acid indigestion Antacids
Pepcid famotidine Blocks the release of gastric acid from stomach cells by attaching to histamine receptors that trigger the release of HCL acid. Peptic ulcers, GERD H2-Receptors Antagonist
Protonix pantoprazole The enzyme HydrogenPotassium ATPase in the stomach maintains the acidity of gastric secretions. PPIs block the enzyme and reduce stomach acidity GERD, Esophagitis, Gastritis, Hypersecretory conditions Proton Pump Inhibitors (PPI)
Flagyl metronidazole kills H. Pylori bacteria, neutralizes stomach acid and/or decreases acid production Combination of: (1) Antibiotics - to kill H. Pylori bact. (2) H2 Receptor Antagonists – decrease acid production (3) Proton Pump Inhibitor Helicobacter Pylori infections, Peptic ulcers caused by H. pylori, Gastritis, Gastric cancer H. Pylori Agents
Pancrease pancrelipase Mimics the action of pancreatic enzymes. Breaks down food in the small intestines to facilitate the absorption of nutrients. Malabsorption syndrome, Pancreatic insufficiency Pancreatic enzymes
Actigall ursodiol Bile acid that dissolves gallstones. Reduces the amount of cholesterol produced by the liver and absorbed by the intestines to prevent the formation of additional Cholelithiasis (gallstones) Gallstone Dissolution Agents
Zofran ondansetron Increases peristalsis (contractions) in the GI tract. Increases the pressure closing the esophageal sphincter = prevents vomiting. Increases the rate the stomach empties. Nausea and Vomiting Antiemetics
Phenergan promethazine Increases peristalsis (contractions) in the GI tract. Increases the pressure closing the esophageal sphincter = prevents vomiting. Increases the rate the stomach empties. Nausea and Vomiting Antiemetics
Lomotil diphenoxylate w/atropine Slows peristalsis of GI muscles. Slower transit time allows for improved water absorption in the colon. Diarrhea Antidiarrheal Agents
Lactinex lactobacillus acidophilus Slows peristalsis of GI muscles. Slower transit time allows for improved water absorption in the colon. Diarrhea Antidiarrheal Agents
Gas-X simethicone Reduces the surface tension of gas bubbles causing them to break or turn into a foam that can be eliminated easily by burping or passing flatus. Excessive internal gas, Bloating, Post-op gas pains Antiflatulents
Phillips Milk of Magnesia magnesium hydroxide Causes retention of fluids in the colon which causes the colon to stretch and increases peristaltic activity Constipation Saline Laxatives
Enulose lactulose Draws water into the colon and stimulates evacuation of bowel contents. Also softens the stool by adding water to colon contents. Constipation Osmotic Laxatives
Fleet Glycerin Suppositories glycerin Draws water into the colon and stimulates evacuation of bowel contents. Also softens the stool by adding water to colon contents. Constipation Osmotic Laxatives
MiraLax polyethylene glycol 3350 Increases the osmolarity of bowel contents thus drawing large amounts of water into the intestines and promoting peristalsis and elimination. GI Pre-op preparation, Constipation Bowel Evacuants
Reglan metoclopramide Increases peristalsis (contractions) in the GI tract. Increases the pressure closing the esophageal sphincter = prevents acid reflux. Increases the rate the stomach empties GERD Prokinetic Agents
Created by: aaishat
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