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Diabetic meds 38
| Term | Definition | |
|---|---|---|
| Regular insulin | Humulin R Novolin R | |
| Combination insulin | humalog 50/50 Humalog 75/25 Novolog 70/30 Humulin 70/30 Novolin 70/30 | |
| Glucagon | Released from alpha cells into it is slits of longer hands in response to low blood glucose causes immediate mobilization of glycogen stored in the liver and raise his blood glucose levels | |
| Sulfonylureas | Chlopropamide- First generation binds to potassium channels on pancreatic beta cells may improve insulin binding to insulin receptors and increase number of insulin receptors glyburide second generation first generation associated with cardiac disease | |
| Sodium glucose cotransporter 2 inhibitors | Canagliflozin-sodium glucose co-transporter inhibitor increases the excretion of glucose from the kidney leading to lowered serum glucose levels | |
| Biguanide | Metformin-May increase the peripheral use of glucose increase production of insulin decrease hepatic glucose production and alter intestinal absorption of glucose Adverse reactions hypoglycemia lactic acidosis G.I. upset nausea anorexia diarrhea heartburn | |
| Dpp4 inhibitor | Sitagliptin- slows breakdown of GLP-1 which leads to increased insulin release, decreased glucagon release and slowed GI absorption | |
| Glucagon | Increase the blood glucose levels by decreasing insulin release and accelerating the breakdown of glycogen in the liver to release glucose D-D thiazide diuretic, anticoagulant | |
| Glucagon Polypeptide receptor agonists | Liraglutide- acts on beta cells to increase insulin release decrease glucagon release slows GI absorption and stimulates the satiety center to decrease appetite | |
| Lantus | Glargine Long | |
| Toujeo | Glargine Long | |
| Levemir | Detemir Long | |
| Lispro | Humalog short | |
| Novolog | Aspart short | |
| Apidra | Glulisine short | |
| Humulin R | Regular | |
| Novolin R | Regular |