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Hypercholesterolemia
Drug Class ( High Cholesterol)
| Question | Answer |
|---|---|
| Statins | atorvastatin (Lipitor) lovastatin (Mevacor) pravastatin (Pracachol) rosuvastatin (Crestor) simvastatin (Zocor) |
| atorvastatin (Lipitor) lovastatin (Mevacor) pravastatin (Pracachol) rosuvastatin (Crestor) simvastatin (Zocor) | Contraindicated clients with liver disease or failure Can cause breakdown of muscle (rhabdomyolysis) muscle aches, weakness. Grapefruit Juice must be avoided Monitor for reddish, dark urine (signs of muscle breakdown) |
| atorvastatin (Lipitor) lovastatin (Mevacor) pravastatin (Pracachol) rosuvastatin (Crestor) simvastatin (Zocor) | Oral, Blocks a substance the body needs to make cholesterol |
| Ezetimibe (Zetia) | Oral, reduces cholesterol absorption in the small intestine Can cause muscle pain, joint pain and diarrhea |
| Bile acid sequestrants | cholestyramine (Questran) colesevelam (Welchol) |
| cholestyramine (Questran) colesevelam (Welchol) | Oral tablet or powder Disrupts the fat absorption process in the intestine |
| cholestyramine (Questran) colesevelam (Welchol) | Powder form is mixed with water before administering Can cause constipation, abdominal pain, cramping and bloating All other oral medications should be administered 1-4 hours before or 4-6 hours after these medications |
| Fibrates | fenofibrate (Tricor) gemfibrozil (Lopid) |
| fenofibrate (Tricor) gemfibrozil (Lopid) | Oral, decreases triglyceride levels ( a type of fat in the blood stream) |
| fenofibrate (Tricor) gemfibrozil (Lopid) | Can increase liver enzymes Increased risk of muscle breakdown/pain when combined with a statin Can also cause abdominal pain and indigestion |
| Niacin | Niaspan (extended release niacin) |
| Niaspan (extended release niacin) | Oral, reduces triglycerides and LDL cholesterol (bad cholesterol) |
| Niaspan (extended release niacin) | Can include flushing, itching, nausea, vomiting, diarrhea, gout and cough Can elevate liver enzymes Must be used with extreme caution if client takes warfarin. Can increase bleeding risk. |
| Fish Oils | omega-3 acid ethyl esteres (Lovaza) icosapent ethyl (Vascepa) |
| omega-3 acid ethyl esteres (Lovaza) icosapent ethyl (Vascepa) | Oral, Reduces triglyceride levels |
| omega-3 acid ethyl esteres (Lovaza) icosapent ethyl (Vascepa) | Can cause a bad aftertaste, burping, stomach discomfort, vomiting, and increased flatulence ( Gas) |
Created by:
Rosayg26
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