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Seizures

NERVOUS SYSTEM: Drugs given to prevent or control seizures

QuestionAnswer
Diazepam (Valium) Tranquilizer with potent antiseizure properties. Administered IV. Lasts 3-4 hours.
Pentobarbital (Nembutal) Short-acting barbiturate that is effective for controlling seizures. Administered IV. Lasts 1-3 hours.
Phenobarbital (Luminal, Solfoton) Antiseizure drug available in oral for dogs and cats and injectable forms for horses.
Primidone (Mylepsin, Neurosyn) A portion of the dose is metabolized to phenobarbital by the liver.
Bromide Old anticonvulsant mainly used today as an adjunct to phenobarbital or primidone therapy
Gabapentin (Neurontin) May be used as an adjunctive treatment of seizures that are difficult to control, as well as for partial complex seizures or pain control.
Levetiracetam (Kappra) May be useful as an adjunctive for refractory canine epilepsy
Zonisamide (Zonegran) Used similar to levetiractam
Adverse side effects Drowsiness, CNS depression, anxiety, agitation, polyuria, polydipsia, hepatotoxicity
Created by: lauren97
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