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PT.1 KEY TERMS Ch.5

Pharmacology Ch.5

TermDefinition
hepatitis inflammation of the liver
boost one drug given to increase the serum concentration of another drug
CD4 cells cells that underlie the immune response in the body
latency the ability of a virus to lie dormant and then, under certain conditions, reproduce and again behave like an infectious agent, causing cell damage
generalized viral infection an infection that has spread to other tissues by way of the bloodstream or the CNS
immunization the process whereby a person acquires resistance to an infectious disease
antiviral an agent that prevents virus replication in a host cell without interfering with host's normal function
capsid a protein shell that surrounds and protects the nucleic acid within a virus particle
chronic viral infection an infection that has a protracted course with long periods of remission interspersed with recurrence
desiccant a substance that maintains dryness
influenza the flu, a common viral infection
cocktail different drugs used in conjunction as drug therapy
immunocompromised having a deficiency in the immune system response
inactivated vaccines vaccines that use pathogens that have been killed with chemicals, heat, or radiation
interferon a substance that exerts virus-nonspecific but host-specific antiviral activity by inducing genes coding for antiviral proteins that inhibit the synthesis of viral RNA
fusion inhibitor a drug that prevents HIV from entering the immune cells
acute viral infection an infection that quickly resolves with no latent infection
active immunity the process by which a person's body makes its own antibodies to a pathogen
envelope membrane surrounding the capsid in some viruses and carrying surface proteins that attach to cell surface receptors
antiretroviral a drug that limits the progression of HIV or other retrovirus infections
chemokine coreceptor antagonist a drug that prevents a strain of HIV from attaching to an immune system cells
immunoglobulin an antibody that reacts to a specific foreign substance or organism and may prevent its antigen from attaching to a cell receptor or may destroy the organism
genital herpes a sexually transmitted disease caused by the herpes simplex virus; characterized by lesions the cause a burning sensation
retrovirus a virus that can copy its RNA genetic information into the host's DNA
live attenuated vaccines vaccines that use live but weakened pathogens to produce an immune response
naked virus a virus without an envelope covering the capsid
passive immunity immunization when antibodies are transferred to the fetus during pregnancy
vaccine a substance used to stimulate the production of antibodies and provide immunity
virion an individual viral particle capable of infecting a living cell; consists of nucleic acid surrounded by a capsid (protein shell)
prodrug a compound that, on administration and chemical conversion by metabolic processes, become an active pharmacologic agent
virus a minute infectious agent that does not have all the components of a cell and thus can replicate only within a living host cell
reverse transcriptase a retroviral enzyme that makes a DNA copy from an RNA original
vaccination the introduction of a vaccine, a component of an infectious agent, into the body to produce immunity to the actual agent
local viral infection a viral infection affecting tissues of a single system such as the respiratory tract, eye, or skin
travel immunization clinic clinical sites that provide immunizations and advice about what vaccines ae needed
travel vaccines vaccines given prior to travel to allow the immune system time to confer to full immunity
uncoating the removal of the virus capsid proteins to expose the nucleic acid
vaccine information statement (VIS) a list of risks associated with vaccination
Created by: Jaghuri
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