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PT.1 KEY TERMS Ch.5
Pharmacology Ch.5
| Term | Definition |
|---|---|
| hepatitis | inflammation of the liver |
| boost | one drug given to increase the serum concentration of another drug |
| CD4 cells | cells that underlie the immune response in the body |
| latency | the ability of a virus to lie dormant and then, under certain conditions, reproduce and again behave like an infectious agent, causing cell damage |
| generalized viral infection | an infection that has spread to other tissues by way of the bloodstream or the CNS |
| immunization | the process whereby a person acquires resistance to an infectious disease |
| antiviral | an agent that prevents virus replication in a host cell without interfering with host's normal function |
| capsid | a protein shell that surrounds and protects the nucleic acid within a virus particle |
| chronic viral infection | an infection that has a protracted course with long periods of remission interspersed with recurrence |
| desiccant | a substance that maintains dryness |
| influenza | the flu, a common viral infection |
| cocktail | different drugs used in conjunction as drug therapy |
| immunocompromised | having a deficiency in the immune system response |
| inactivated vaccines | vaccines that use pathogens that have been killed with chemicals, heat, or radiation |
| interferon | a substance that exerts virus-nonspecific but host-specific antiviral activity by inducing genes coding for antiviral proteins that inhibit the synthesis of viral RNA |
| fusion inhibitor | a drug that prevents HIV from entering the immune cells |
| acute viral infection | an infection that quickly resolves with no latent infection |
| active immunity | the process by which a person's body makes its own antibodies to a pathogen |
| envelope | membrane surrounding the capsid in some viruses and carrying surface proteins that attach to cell surface receptors |
| antiretroviral | a drug that limits the progression of HIV or other retrovirus infections |
| chemokine coreceptor antagonist | a drug that prevents a strain of HIV from attaching to an immune system cells |
| immunoglobulin | an antibody that reacts to a specific foreign substance or organism and may prevent its antigen from attaching to a cell receptor or may destroy the organism |
| genital herpes | a sexually transmitted disease caused by the herpes simplex virus; characterized by lesions the cause a burning sensation |
| retrovirus | a virus that can copy its RNA genetic information into the host's DNA |
| live attenuated vaccines | vaccines that use live but weakened pathogens to produce an immune response |
| naked virus | a virus without an envelope covering the capsid |
| passive immunity | immunization when antibodies are transferred to the fetus during pregnancy |
| vaccine | a substance used to stimulate the production of antibodies and provide immunity |
| virion | an individual viral particle capable of infecting a living cell; consists of nucleic acid surrounded by a capsid (protein shell) |
| prodrug | a compound that, on administration and chemical conversion by metabolic processes, become an active pharmacologic agent |
| virus | a minute infectious agent that does not have all the components of a cell and thus can replicate only within a living host cell |
| reverse transcriptase | a retroviral enzyme that makes a DNA copy from an RNA original |
| vaccination | the introduction of a vaccine, a component of an infectious agent, into the body to produce immunity to the actual agent |
| local viral infection | a viral infection affecting tissues of a single system such as the respiratory tract, eye, or skin |
| travel immunization clinic | clinical sites that provide immunizations and advice about what vaccines ae needed |
| travel vaccines | vaccines given prior to travel to allow the immune system time to confer to full immunity |
| uncoating | the removal of the virus capsid proteins to expose the nucleic acid |
| vaccine information statement (VIS) | a list of risks associated with vaccination |