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Rad bio chapter 9

QuestionAnswer
radiation induced damage at the cellular level may lead to measurable somatic & hereditary damage in the living organism Late Effects
Measurable late (stochastic) biologic damage includes cataracts, leukemia, & genetic mutations
a science that deals with the incidence distribution and control of disease in a population epidemiology
observed effects of radiation exposure incidence of a disease & severity of an effect
dose-response curve linear or nonlinear; threshold dose or non-threshold dose
created linear-quadratic curve then made linear curve (leukemia, breast cancer, & genetic damage) Committee on the biological Effects of Ionizing Radiation (BEIR) 1980
when radiation exposure causes biologic damage somatic effects
the probability that the effect happens depends upon the received dose, but not severity stochastic effects
both the probability and the severity of the effect depend upon the dose (cataracts) tissue reactions
cataract formation, fibrosis, organ atrophy, loss of parenchymal cells, reduced fertility, sterility late tissue reactions
effects of radiation on the embryo-fetus in utero that depend on the fetal stage of development and the radiation dose received teratogenic effect
carcinogenesis stochastic event
cataract genesis late tissue reaction
embryologic effect (birth defects) stochastic event
the radiation dose that causes the number of spontaneous mutations occurring in a given generation to increase to two times their original number doubling dose concept
what is the radiation doubling equivalent dose for humans 1.56 Sv
Created by: gnteumac
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