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Unit 2 2514

Antidiarrheals

QuestionAnswer
What is a potentially dangerous adverse effect of bismuth subsalicylate (pepto-bismol)? Can increase bleeding time, affects platelets much like aspirin. Cannot be used for bleeding stomach ulcers
Can antidiarrheal medications cause constipation? Yes, they can.
What is the mechanism of action for bismuth subsalicylate (pepto-bismol)? Coats the walls of the GI tract, binds to causative bacteria or toxin which is then eliminated in stool
What is an important aspect of patient teaching regarding stools when a client is taking bismuth subsalicylate (pepto bismol)? Stools may be dark or black with this medication
Name two opioid medications used to treat diarrhea. Diphenoxylate with atropine (Lomotil), and Loperamide (Immodium).
Would an opioid like morphine or fentanyl be used to treat diarrhea? No. We have opioid analogues that do not provide pain relief in the doses used to treat diarrhea
What is the mechanism of action of opioids when used for diarrhea? They activate opioid receptors in the GI tract to slow motility, decrease secretions into the intestines, and increase absorption of fluid and sodium from the GI tract.
What are some of the other effects of bismuth subsalicylate that are not as dangerous as increasing bleeding time? Constipation, confusion, twitching, hearing loss, tinnitus, metallic taste, blue gums.
What is the effect of bismuth subsalicylates to the kidneys? They are nephrotoxic due to aspirin like properties.
Which class of antidiarrheal medications can be used to relieve tinnismus? Opiate - Atropine (Lomotil), Loperamide (Immodium)
A person having IBD may be at risk for what complication when using opioid nonspecific antidiarrheals? They may cause megacolon toxicity in patient with IBD
Created by: Shamilla
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