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Alzheimer’s
| Question | Answer |
|---|---|
| What is the pathophysiology of Alzheimer’s ? | Unknown cause with possible genetic contribution. Beta amyloid plaques develop throughout the brain |
| What are some modifiable risk factors of Alzheimer’s? | HTN, DM, obesity, smoking, sedentary lifestyle, hypothyroidism, Afib |
| What are some non modifiable risk factors of Alzheimer’s? | Age >65, stroke, metabolic syndrome, depression, severe head trauma, Down’s syndrome, African American, APOE gene polymorphism |
| What are some social factors that contribute to AD? | Isolation, decreased cognitive stim, decreased level of education |
| True or false. AD is a diagnosis of exclusion. There are no tests to confirm the disease | True |
| What are the hallmark signs of AD? | Cortical atrophy, beta amyloid plaques, tau proteins (all confirmed post mortem) |
| How is AD different from dementia? | - AD: specific brain disease that accounts for 60-80% of dementia cases - Dementia: general term for sx like decline in memory, reasoning, or other thinking |
| What are some early signs of AD? | Word finding difficulty, mood swings, impaired attention, confusion, memory issues, poor problem solving, rapid changes in awareness of place and time, visual agnostics, expressive aphasia, etc |
| What is the goal of PT for Alzheimer’s? | Support and safety: take note of AMS, keep commands/ cues simple, don’t overstimulate, don’t leave unsupervised, calm/ reassuring demeanor |
Created by:
aaussems
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