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BrainTumors/Seizures

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This is a seizure that starts in one area of the brain. The person remains alert + able to interact. Lasts < 2 min Focal (Onset) Aware Seizure
This seizure starts in one area or side of the brain. A person is not aware of their surrounding during it. Typically lasts 1-2 minutes. Focal (Onset) Impaired Awareness Seizure
This type of seizure is usually characterized by an “aura” beforehand. Focal Impaired Awareness
This type of seizure includes automatisms (lip smacking, picking at clothes, fumbling) Focal Impaired Awareness
During this type of seizure, a person loses consciousness, muscles stiffen and jerking movements are seen. Tonic- clonic
This type of seizure usually lasts 1-3 minutes. Tonic clonic
A tonic clonic seizure lasting ____ minutes is a medical emergency. 5 minutes
This type of seizure causes lapses in awareness, sometimes with staring. They begin and end abruptly, lasting only a few seconds. Absence Seizure
These seizures are more common in children. Absence seizures
During this type of a seizure, a person suddenly loses muscle tone so their head or body may go limp. Atonic seizures
These seizures are known as “drop attacks” Atonic seizures
What’s the difference between a focal onset and a generalized onset seizure? Focal: start in one area or group of cells in one side of the brain Generalized: affects both sides of the brain
What are some other medical causes of seizure (other than epilepsy)? Acute illness/ fever, vascular, trauma, toxic/ metabolic
This is a growth of abnormal cells that have formed in the brain. Brain tumor
True or false. Benign brain tumors are not cancer but they still can cause symptoms and require treatment. True. It is still a serious medical condition. For that reason, they are more often called “non malignant” to clarify that they are made of non-cancerous cells
True or false. 1/2 of brain tumors are malignant. False. <1/3
True or false. Malignant brain tumors generally grow faster and more aggressively than non- malignant True
Based on the WHO Tumor Grades, this grade tumor is the least malignant. Associated with long-term survival. Grow slowly, almost normal appearance on microscope Grade I
Based on the WHO Tumor Grades, this grade tumor is slow growing but can look slightly abnormal under the microscope. Some can spread, sometimes as a higher grade. Grade II
Based on the WHO Tumor Grades, this grade tumor is malignant, actively reproducing abnormal cells which grow into nearby brain tissue. Tend to reoccur. Grade III
Based on the WHO Tumor Grades, this grade tumor is the most malignant, reproduce rapidly and have a bizarre appearance under the microscope. These tumors form new blood vessels. Grade IV
What is the median age at diagnosis for all primary brain tumors? 60 y/o
What is an environmental risk factor for developing a brain tumor? -Ionizing radiation (X-rays)
Are brain tumors usually genetic? No- only ~5-10% of brain tumors are hereditary
These brain tumors arise from the supportive tissues in the brain and SC Gliomas
This type of brain tumor is from the dura or arachnoid mater. Meningioma
What are the 4 types of GLIOMAS? 1. Astrocytoma 2. Oligodendroglioma 3. Ependymoma/ Ependymoblastoma 4. Medulloblastoma
This is the most common type of brain tumor in 30-50 year olds. Astrocytoma
This type of tumor is highly malignant. It is the most common tumor (21% of all adults) Gliobastoma Multiforme
What is the prognosis for a GBM? 12-14 months (<20% after 1 yr and ~2% after 5 yrs)
This type of tumor involves the oligodendrocytes, is slow growing and progresses over years. Most common in 40-60 y/o. Oligodendroglioma
What is the prognosis for an oligodendroglioma? 9 years
True or false. GBMs and oligodendrogliomas affect more women than men. False! men > women (2:1)
What is the tell tale sign for an oligodendroglioma? Seizures
This tumor accounts for 2% of all primary tumors. It arises from cells in the lining of the ventricles. Posterior fossa of SC with sx that can resemble SCI. Ependymoma/ Ependymoblastoma
This is a fast growing tumor that arises from the cerebellum. Medulloblastoma
This tumor is most common in children <10 years old. (18% of all pediatric tumors) Medulloblastoma
What is the prognosis for a medulloblastoma? Children: 70-80% have 5 yr survival Adults: 55-60% have 5 yr survival
This tumor can be benign or malignant, incidence increases with age, and many pts are asymptomatic so usually found incidentally. Meningioma
These two tumors are more common in females. - Meningioma: females > males (2:1) - pituitary adenoma: females > males (2.25%)
When this tumor approaches the optic chiasm , pts may lost their vision. Pituitary adenoma
This type of tumor affects cranial or spinal nerves. There is usually good prognosis but functional impairments may remain. Schwannoma
What nerve is a Schwannoma most likely to occur? CN VIII (acoustic neuroma)
What is a metastatic brain tumor? A tumor that occurs in the brain due to cancer cells that spread from another part of the body. (Breast, lung, melanoma, colorectal, genitourinary)
Where do metastatic brain tumors mostly occur? Frontal lobe
What is the prognosis for a metastatic brain tumor? 1 month without treatment 6 months with treatment (radiation, steroids) Surgical resection can extend to 16 months
Created by: aaussems
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