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Drug Test #4

QuestionAnswer
What is a common name fore HMG CoA Reductase Inhibitors? Statins
What do statins treat? Hyperlipidemia
Words that end in -ase are what? enzymes
What are HMG CoA Reductase? enzymes involved in the final step of cholesterol synthesis
What do statins do? Inhibit HMG CoA reductase (therefore, inhibit final step in synthesis of cholesterol)
What do statins do with LDL? they increase clearance of LDL (low density lipoproteins : "lousy" cholesterol
When are statins usually taken? once daily (usually evening or bedtime)
Adverse reactions of Statins? myositis *inflammation of muscle*, Rhabdomyolysis *breakdown of muscle tissue*, muscle cramps/pain, liver dysfunction
What is the generic of Crestor? rosuvastatin
What is the generic of Lescol? fluvastatin
What is the generic of LIpitor? atorvastatin
What is the generic for Mevacor? lovastatin
What is the generic for Pravachol? pravastatin
What is the generic for Zocor? simvastatin
Dosages for rosuvastatin tablets-5mg, 10mg, 20mg, 40mg
Dosages for fluvastatin capsules-20mg, 40mg - extended release tabs 80mg
Dosages for atorvastatin tablets- 10mg, 20mg, 40mg, 80mg
Dosages for lovastatin tablets- 20mg, 40mg
Dosages for pravastatin tablets- 10mg, 20, 40mg
Dosages for simvastatin tablets 5mg, 10mg, 20mg, 40mg, 80mg
Which statins should you avoid grapefruit juice with? atorvastatin, lovastatin, simvastatin
What should you avoid with rosuvastatin? antacids containing magnesium
What do antiplatelets treat? myocardial infarction (MI, heart attack) & stroke
How do antiplatelets work? interfere with clot formation process
What do antiplatelets interact with commonly? OTC products
Adverse reaction to all platelets? Bleeding
Signs of internal bleeding are: black, tarry stool, blood in vomit or urine, red or purple spots on skin
What is the generic of Aggrenox? dipyridamole + ASA
What is the generic of Aspirin? acetylsalicylic acid (ASA)
What is the generic ofPersantine? dipyridamole
What is the generic of Plavix? clopidogrel
What is the generic of Ticlid? ticlopidine
What is the generic of Brilinta? ticagrelor
What is the generic of Effient? prasugrel
Dosage for dipyridamole/ASA capsule 200mg/25mg *commonly twice a day*
Which antiplatelets should you take with food? dipyridamole/ASA, ticlopidine, ASA
Dosage for ASA tablets- 80mg chewable, 81mg *commonly once per day*
Dosage for dipyridamole tablets & injections are available
Dosage for clopidogrel tablets- 75mg, 300mg *ODB does not cover 300mg tabs*
Dosage for ticlopidine tablets-250mg
Dosage for ticagrelor tablets - 90mg
Which antiplatelet should you not discontinue use? Ticagrelor (Brilinta)
Dosage for prasugrel tablets -10mg
Which antiplatelet should you take on an empty stomach? dipyridamole
What should you avoid if taking ASA? other NSAID or ASA containing products
Which antiplatelet should be dispensed in it original container? Aggrenox
What do anticoagulants treat? myocardial infarction (MI, heart attack) & stroke
How do anticoagulants work? inhibit clotting factors & prevent clot formation
Common adverse reaction of anticoagulants? bleeding
Common Aux labels needed for anticoagulants: avoid ASA & NSAIDs - do not use OTC without medical supervision
What is the generic for Arixtra? fondaparinux
What is the generic for Coumadin? warfarin
What is the generic for Fragmin? dalteparin
What is the generic for Hepalean heparin
What is the generic for Innohep? tinzaparin
What is the generic for Lovenox? enoxaparin
What is the generic for Pradaxa? dapigatran
Which anticoagulants come in oral form? warfarin, dabigatran
Dosage for warfarin tablets- 1mg,2mg,2.5mg,3mg,4mg,5mg,10mg *commonly daily, can be a few days per week*
Dosage for dabigatran capsules-110mg, 150mg *commonly twice daily*
Common form of administration for most anticoagulants? injectable or solution for injection
What is an overdose of warfarin treated with? Vitamin K
What is an overdose of heparin treated with? protamine sulfate
Which injectable anticoagulant is usually dosed every 12 hours or every 24 hours? enoxaparin
Created by: melissa.perry
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