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Pharmacology - Ch.2

terminology

QuestionAnswer
Bioavailability Percentage of the drug dosage that is absorbed.
Drug Absorption Entrance of a drug into the bloodstream from its site of administration.
Drug Addiction Condition of drug abuse and drug dependence that is characterized by compulsive drug behavior.
Drug Dependence Condition of reliance on the use of a particular drug, characterized as physical and/or psychological dependence.
Drug Distribution Passage of a drug from the blood to the tissues and organs of the body.
Drug Microsomal Metabolizing System (DMMS) Group of enzymes located primarily in the liver that function to metabolize (biotransformation) drugs.
Drug Tolerance Decreased drug effect occurring after repeated drug administration.
Enzyme Induction Increase in the amount of drug-metabolizing enzymes after repeated administration of certain drugs.
Enzyme Inhibition Inhibition of drug-metabolizing enzymes by certain drugs.
First-pass Metabolism Drug metabolism that occurs following oral absorption from the GI tract.
Half-life Time required for the body to rid itself of half of the drug dosage that was absorbed (percent bioavailability)
Individual Variation Difference in the effects of drugs and drug dosages from one person to another.
Intramuscular (IM) Injection Route of drug administration; drug is injected into gluteal or deltoid muscles.
Intravenous (IV) Injection Route of drug administration; drug is injected directly into a vein.
Loading Dose Initial drug dose administered to rapidly achieve therapeutic drug concentrations.
Maintenance Dose Dose administered to maintain drug blood levels in the therapeutic range.
Oral Administration Route of drug administration by way of the mouth through swallowing.
Parenteral Administration Route of drug administration that does not involve the gastrointestinal (GI) tract.
Created by: rstacey1
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