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GI 1
Gastroenterology 1
| Generic Name | Brand Name | Pharmacologic Category | Common Indications | Essential Knowledge |
|---|---|---|---|---|
| lubiprostone (PO) | Amitiza | Chloride channel activator | IBS with constipation, chronic constipation | nausea, diarrhea, HA, dyspnea, CI in mechanical bowel obstruction |
| dexamethasone (PO, IV) | DexPak, DoubleDex | Corticosteroid | Inflammatory diseases, cerebral edema | hyperglycemia, increased appetite with weight gain, behavioral disturbances, osteoporosis (chronic), Cushing's syndrome (chronic), risk of adrenal suppression with prolonged use. |
| methylprednisolone (PO, IV) | Medrol | Corticosteroid | Inflammatory diseases, COPD exacerbation, asthma exacerbation, acute gout | hyperglycemia, increased appetite with weight gain, behavioral disturbances, osteoporosis (chronic), Cushing's syndrome (chronic), risk of adrenal suppression with prolonged use. |
| prednisolone (PO) | Orapred | Corticosteroid | Inflammatory diseases, COPD exacerbation, asthma exacerbation, acute gout | hyperglycemia, increased appetite with weight gain, behavioral disturbances, osteoporosis (chronic), Cushing's syndrome (chronic), risk of adrenal |
| prednisone (PO) | Deltasone | Corticosteroid | Inflammatory diseases, COPD exacerbation, asthma exacerbation, acute gout | hyperglycemia, increased appetite with weight gain, behavioral disturbances, osteoporosis (chronic), Cushing's syndrome (chronic), risk of adrenal |
| hydrocortisone (rectal, IV) | Rectal: Anusol-HC, Anucort-HC IV: Solu-Cortef | Corticosteroid | Hemorrhoids | hyperglycemia, increased appetite with weight gain, behavioral disturbances, osteoporosis (chronic), Cushing's syndrome (chronic), risk of adrenal |
| metoclopramide (PO, IV) | Reglan | Dopamine (D2) antagonist | Gastroparesis, GERD, N/V | drowsiness, dystonia, akathisia, EPS, QTc prolongation, US BOXED WARNING: tardive dyskinesia |
| prochlorperazine (PO, IV) | Compazine | Dopamine (D2) antagonist | N/V | drowsiness, dizziness, xerostomia, blurred vision, constipation, QTc prolongation, US BOXED WARNING: increased risk of death in elderly with dementia related psychosis, do not give IV push |
| promethazine (PO, IM, IV) | Phenergan | Histamine (H1) blocker | motion sickness, nausea, vomiting | drowsiness, dry mouth, blurred vision, QTc prolongation, US BOXED WARNING: potential fatal respiratory depression in patients less than 2 |
| lactulose (PO) | Enulose, Kristalose, Constulose | Laxative | Constipation, hepatic encephalopathy | abdominal cramps, abdominal distention, diarrhea, flatulence |
| ondansetron (PO, IV) | Zofran, Zofran ODT | Selective serotonin (5-HT3) antagonist | N/V | HA, fatigue, constipation, diarrhea, QTc prolongation |
| diphenoxylate and atropine (PO) | Lomotril | Opioid agonist and anticholinergic | Diarrhea | nausea, drowsiness, dizziness, xerostomia, tachycardia, urinary retention |
| mesalamine (PO, rectal) | Asacol, Canasa, Lialda | 5-aminosalicylic acid derivative | Crohn's disease, ulcerative colitis | eructation, abdominal pain, constipation |
| dicyclomine (PO) | Bentyl | Anticholinergic | IBS | constipation, xerostomia, blurred vision, dizziness |
| hyoscyanmine (PO) | Anaspaz, Levbid | Anticholinergic | Diarrhea | constipation, xerostomia, blurred vision, dizziness |
Created by:
Rosa Barrett
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