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Drug Test #3
Green Block #3 - info quiz
| Question | Answer |
|---|---|
| Diuretics help treat? | hypertension |
| Diuretics increase elimination of? | water and electrolytes |
| Increased urination | adverse reactions to diuretics |
| Photosensitivity (Thiazide & Loop diuretics) | adverse reactions to diuretics |
| Avoid prolonged exposure to sun (Thiazide & Loop diuretics) | auxiliary labels for diuretics |
| May be advisable to eat bananas or drink orange juice (Thiazide & Loop diuretics) | auxiliary labels for diuretics |
| Decrease vasoconstriction, peripheral resistance, blood pressure | Thiazide Diuretics |
| Weak acids; Highly protein bound | Thiazide Diuretics |
| Act in distal convoluted tubule | Thiazide Diuretics |
| May rise serum glucose | Thiazide Diuretics |
| Dehydration; Electrolyte deficiencies | adverse reactions to thiazide diuretics |
| Excess uric acid & gout flare-ups | adverse reactions to thiazide diuretics |
| Take in morning to avoid ... | nocturia |
| Effect reduced when taken concurrently with ... | NSAIDs |
| Tablets – 25mg, 50mg Common Doses: 12.5-50mg once daily (QAM) | Hydrodiuril |
| Hydrodiuril | hydrochlorothiazide (HCTZ) |
| Tablets – 1.25mg, 2.5mg Commonly dosed once daily (QAM) | Lozide |
| Lozide | indapamide |
| Tablets – 2.5mg Commonly dosed once daily, or a few days each week (mornings) | Zaroxolyn |
| Zaroxolyn | metolazone |
| Thiazide diuretics inhibit ___% sodium reabsorption | 5-10 |
| Act in ascending loop of Henle | Loop diuretics |
| Up to 98% protein bound | Loop diuretics |
| Hypokalemia; Dehydration | adverse reaction to loop diuretics |
| Severe hypotension | adverse reaction to loop diuretics |
| Often taken with potassium supplement | Loop diurectics |
| Loop dialectics inhibit ___% sodium reabsorption = Most potent diuretics | 20-30 |
| Hydrodiuril; Zaroxolyn; Lozide | Thiazide diurectics |
| Lasix (class) | Loop diurectic |
| Lasix (generic name) | furosemide |
| Tablets – 20mg, 40mg Commonly doses 1-2 times daily | Lasix |
| Inhibit sodium reabsorption while sparing potassium loss | Potassium Sparing Diuretics/Aldosterone Receptor Antagonists |
| competitive antagonist of aldosterone | Aldactone |
| Hyperkalemia (increased risk when taken with ACEIs); Gynecomastia; Hirsutism | Potassium Sparing Diuretics/Aldosterone Receptor Antagonists |
| Potassium Sparing Diuretics/Aldosterone Receptor Antagonists effectiveness increased when combined with ... | thiazide |
| Potassium Sparing Diuretics/Aldosterone Receptor Antagonists inhibit ___% sodium reabsorption; Less effective than Thiazide & Loop diuretics | 1-3 |
| Aldactone (class) | Potassium Sparing Diuretics/Aldosterone Receptor Antagonists |
| Aldactone (generic name) | spironolactone |
| Tablets – 25mg, 100mg Common doses: 25-100mg once daily | Aldactone |
| Take with Food Avoid salt substitutes and potassium rich diets | Aldactone |
| Cardioglycosides are commonly used to treat? | Heart failure |
| Increase cardiac output & force of myocardial contractions | Cardioglycosides |
| Cardioglycosides have a narrow ___ (lethal dose close to therapeutic dose) | therapeutic index |
| arrhythmias, dizziness, convulsions, delusions, coma | Digitalis toxicity |
| Photophobia; visual disturbances; weakness; gynecomastia | adverse reaction to cardioglycosides |
| Toloxin | Cardioglycosides |
| Toloxin | digoxtin |
| Tablets – 0.0625mg, 0.125mg, 0.25mg Commonly dosed once daily | Toloxin |
| Antiarrhythmics are commonly used to treat | Arrhythmia (Irregular heart rates & rhythms) |
| Other arrhythmias, bradycardia, dizziness, hypotension | adverse reaction to antiarrhythmics |
| Class 1A, 1B, and 1C Antiarrhythmics | Sodium (Na) channel blocker |
| quinidine sulfate; Procan SR | Class IA |
| procainamide | Procan SR |
| Xylocard | Class IB |
| Lidocaine | Xylocard |
| Tambacor; Rhythmol | Class IC |
| propafenone | Rhythmol |
| flecainide | Tambacor |
| Class II | Beta (β) blocker |
| Rhotral, Sectral; Inderal; Sotacor | Beta (β) blocker |
| acebutalol | Rhotral, Sectral |
| propranolol | Inderal |
| sotalol | Sotacor |
| Class III | Potassium (K) channel blocker |
| Cordarone | Potassium (K) channel blocker |
| amiodarone | Cordarone |
| Class IV | Calcium (Ca) channel blocker |
| Isoptin | Calcium (Ca) channel blocker |
| verapamil | Isoptin |
| Decrease in blood volume, peripheral resistance, and cardiac output leads to? | decreased blood pressure |