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MSK 2

Musculoskeletal 2

Generic NameBrand NamePharmacologic CategoryCommon IndicationsEssential Knowledge
methocarbamol (PO) Robaxin Skeletal muscle relaxant Muscle spasm drowsiness
metaxalone (PO) Skelaxin, Metaxall Skeletal muscle relaxant Muscle spasm drowsiness
orphenadrine (PO) Norflex Skeletal muscle relaxant Muscle spasm drowsiness, dizziness, xerostomia, fatigue, use caution in patients with cardiac disease
bupivacaine (IV) Marcaine, Sensorcaine Local anesthetic Epidural anesthesia hypotension US BOXED WARNING: bupivacaine 0.75% should not be used for OB anesthesia due to reports of cardiac arrest and death, high alert medication
lidocaine (transdermal, IV) Transderm: Lidoderm IV: Xylocaine Transderm: topical analgesic IV: antiarrhythmic Transderm: pain IV: ventricular arrhythmias transderm: dermatits, erythema, urticaria, skin depigmentation, skin edema, patch may remain for up to 12 hours, patch may be cut IV: bradycardia, high alert med
allopurinol Zyloprim Xathine oxidase inhibitor gout diarrhea, nausea, rash, leukopenia, thrombocytopenia, rarely severe hypersensitivity syndrome, esp. in certain Asian populations
succinylcholine (IV) Anectine Depolarizing NMBA Neuromuscular blockade for intubation or procedures hyperkalemia, myalgia, malignant hyperthermia (rare) US BOXED WARNING: acute rhabdomyolysis and hyperkalemia leading to cardiac arrest and death in pediatrics with undiagnosed skeletal muscle disease, high alert med.
cyclobenzaprine (PO) Flexeril Skeletal muscle relaxant Muscle spasm drowsiness, dizziness, xerostomia, fatigue, may cause prolonged cardiac, arrhythmias, and tachycardia, CI within 14 days of MAOI inhibitor intake
baclofen (PO) Lioresal Skeletal muscle relaxant Spasticity drowsiness
carisoprodol (PO) Soma Skeletal muscle relaxant Muscle spasm drowsiness, drug abuse potential
Created by: Rosa Barrett
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