click below
click below
Normal Size Small Size show me how
Neuro/Psych III
NEUROLOGICAL AND PSYCHIATRIC DISEASE 3
| Generic Name | Brand Name | Pharmacologic Category | Common Indications | Key Side Effects | US Boxed Warnings | Other Notes |
|---|---|---|---|---|---|---|
| rizatriptan | Maxalt, Maxalt-MLT | Antimigraine | Migraine | |||
| haloperidol (PO, IV, IM) | Haldol | First-generation antipsychotic | Scizophrenia | sedation, EPS, xerostomia, urinary retention, constipation, orthostatic hypotension, weight gain, QTc prolongation | elderly patients with dementia-related psychosis treated with antipsychotic drugs at increased risk of death | |
| clozapine (PO) | Clozaril | Second-generation antipsychotic | Treatment-resistent schizophrenia | sedation, xerostomia, urinary retention, constipation, orthostatic hypotension, sialorrhea | may cause severe neutropenia; orthostatic hypotension, bradycardia, and syncope; may cause seizures; may cause fatal myocarditis and cardiomyopathy; elderly patients with dementia-related psychosis treated w antipsychotic drugs at increased risk of death | risk of neutropenia requires monitoring of absolute neutrophil count (ANC) to receive prescription |
| lurasidone (PO) | Latuda | Second-generation antipsychotic | Schizophrenia, bipolar depression | sedation, EPS, xerostomia, urinary retention, constipation, orthostatic hypotension | antidepressants increase the risk of suicidal thinking and behavior in children, adolescents and young adults; elderly patients with dementia-related psychosis treated with antipsychotic drugs at increased risk of death | |
| aripiprazole (PO, IM) | PO: Abilify IM: Abilify Maintena | Second-generation antipsychotic | Schizophrenia, bipolar disorder, depression, MDD (adjunct to antidepressants) | sedation, EPS, xerostomia, urinary retention, constipation, orthostatic hypotension | antidepressants increase the risk of suicidal thinking and behavior in children, adolescents and young adults; elderly patients with dementia-related psychosis treated with antipsychotic drugs at increased risk of death | |
| quetiapine (PO) | Seroquel, Seroquel XR | Second-generation antipyschotic | Schizophrenia, bipolar disorder, depression, MDD (adjunct to antidepressants) | sedation, EPS, xerostomia, urinary retention, constipation, orthostatic hypotension | antidepressants increase the risk of suicidal thinking and behavior in children, adolescents and young adults; elderly patients with dementia-related psychosis treated with antipsychotic drugs at increased risk of death | |
| olanzapine (PO, IM) | Zyprexa | Second-generation antipyschotic | Schizophrenia, bipolar disorder, depression, MDD (adjunct to antidepressants) | sedation, EPS, xerostomia, urinary retention, constipation, orthostatic hypotension, weight gain | elderly patients with dementia-related psychosis treated with antipsychotic drugs at increased risk of death | |
| risperidone (PO, IM) | PO: Risperdal, Risperdal Consta | Second-generation antipyschotic | Schizophrenia, bipolar disorder, depression, MDD (adjunct to antidepressants) | sedation, EPS, xerostomia, urinary retention, constipation, orthostatic hypotension, weight gain | elderly patients with dementia-related psychosis treated with antipsychotic drugs at increased risk of death | |
| ziprasidone (PO, IM) | Geodon | Second-generation antipyschotic | Schizophrenia, bipolar disorder, depression, MDD (adjunct to antidepressants) | sedation, EPS, xerostomia, urinary retention, constipation, orthostatic hypotension, weight gain | elderly patients with dementia-related psychosis treated with antipsychotic drugs at increased risk of death | |
| paliperidone (PO, IM) | PO: Invega IM: Invega Sustenna | Second-generation antipyschotic | Schizophrenia | sedation, EPS, xerostomia, urinary retention, constipation, orthostatic hypotension, weight gain | elderly patients with dementia-related psychosis treated with antipsychotic drugs at increased risk of death | |
| lithium (PO) | Lithobid | Antimanic agent | Bipolar disorder | tremor, acne, hypothyroidism, weight gain, polyuria, polydipsia | ability to promptly monitor levels is necessary | narrow therapeutic index drug (toxicity may occur at concentrations close to therapeutic range; therapeutic drug monitoring is recommended) |
| sumatriptan (PO, intranasal, subcutaneous, transdermal) | Imitrex | Antimigraine | Migraine | fatigue, somnolence, dizziness, chest tightness |