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lithium
Anxiety/Depression/Bipolar
Term | Definition |
---|---|
lithium Action | known to affect synthesis, release and reuptake of several neurotransmitters in brain, stabilizes postsynaptic receptor sensitivity to neurotransmitters - may also stimulate neuronal growth |
lithium Use | Tx of manic episodes of Bipolar Disorder - dosing considerations |
lithium Adverse effects | Hand Tremors, GI (metallic taste, nausea, diarrhea, weight gain), Polyuria and Polydipsia, Muscular Weakness, Fatigue, Edema |
lithium Contraindications | Pregnancy - CAT D |
lithium RN considerations | therapeutic levels don’t usually occur until 7-10 days , Get baseline lab studies prior to admin & routine serum drug concen. if signs of OD occur - stop taking & contact provider immed |
lithium Pt Teaching | keep scheduled visits for blood tests, do NOT take diuretics w/o consulting provider, including consistent salt & adequate fluid intake (do not alter salt intake and drink 8-12 glasses of fluids dailyTake w/ food/milk avoid excessive caf. bev |
-acute mania serum drug level -maintenance therapy | -1.0-1.5 mEq/L -0.6-1.2 mEq/L |