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Module 3 Final
Pharmacology
| Term | Definition |
|---|---|
| cholingergic drugs (increase acetylcholine) | bethanechol pilocarpine metoclopramide donepezil pyrostigmine physostigmine |
| cholinergic crisis (dumbbells) | Diaphoresis urination miosis bradycardia bronchoconstriction emesis lacrimation lethargy salivation |
| edrophonium | Tensilon test for Myasthenia Gravis |
| anti-cholinergic drugs | atropine |
| anti-cholinergic antidote | Physostigmine |
| cholinergic drugs mimic | PNS "rest and digest" indicated for urinary retention glaucoma |
| antidote for cholinergic crisis | Atropine |
| antidote for anticholinergics | Physostigmine |
| cholinergic drugs are contraindicated in | asthma/COPD (bronchocontriction) |
| Pilocarpine (Cholinergic) | constrict pupils |
| Bethanechol (cholinergic) | contricts/tones bladder- free to pee |
| Metochlopramide cholinergic | speeds up gastric emptying |
| rest and digest (wet) cholinergic drugs | increase salivation increase gastric secretion increase peristalsis HR decreases pupils constrict bronchials contrict bladder contracts- free to pee |
| anti-cholinergic effects (fight or flight) mimics CNS | decrease secretions- dry can't see, can't pee, can't spit, can't poop |
| Scopolamine (Anticholinergic) | patch behind ear used to treat motion sickness and preoperatively to prevent aspiration |
| Benztropine (Anti Parkinson Drug) | treat Parkinson's (decrease tremors and rigidity) treat drug induced EPS |
| Atropine (anticholinergic) | preoperatively to reduce secretions and motion sickness |
| anticholinergic toxicity | "Hot as a hare (temp) red as a beet (flushing) dry as a bone mad as a hatter (confusion) blind as a bat (dilated pupils)." treat with physostigmine |
| anticholinergic effects can't see, can't pee, can't spit, can't poop means | dilated pupils, urinary retention, dry mouth & skin, decreased GI motility |
| another word for pupil dilation (anticholinergic effect) | mydriasis |
| anitcholinergic drugs are contraindicated in | myasthenia gravis (would make weaker) and glaucoma |
| signs that anti parkinson drugs not working | symptoms not controlled: rigidity mask stooped tremors pill rolling |
| End of dose/ on- off syndrome | drugs stop working close to the time of the next scheduled also progression of disease- severe symptoms |
| MAOIs used to treat parkinson's | selegiline and rasagiline Cheese effect - tyramines |
| Tolterodine (anticholinergic) is used to treat | urinary frequency urgency and incontinence |