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Ch 12 terms

aseptic technique and compounding, pharm tech

anteroom the room adjacent to the "clean room" used for donning all personal protective equipment (PPE) and wiping down all supplies that will be used in the compounding area
aseptic technique the procedures used to eliminate the possibility of a drug becoming contaminated with microbes or particles
beyond-use date (BUD) defined by USP <797> as the date or time after which a compounded sterile preparation (CSP) shall not be administered, stored, or transported; it is determined from the date the preparation is compounded
biological safety cabinet (BSC) a vertical flow hood that should be used for making hazardous sterile preparations in the clean room
compounding aseptic containment isolator (CACI) ISO Class 5 compounding area used to prepare hazardous drugs
clean room in pharmacy, a contained and controlled environment in the pharmacy that has a low level of environmental pollutants (i.e. dust, airborne, microbes, aerosol particles, and chemical vapors); the clean room is used for preparing sterile medication products
compounded sterile preparations (CSPs) preparations prepared in a sterile environment using non-sterile ingredients or devices that must be sterilized before administration
critical site any surface or area exposed to first air, which is exposed or at risk for touch, or direct air (i.e. vial tops, open ampules, needle hubs, or injection ports)
gauges the sizes of needle openings
first air air exiting the HEPA filter in a unidirectional air stream
hazardous drug any drug that has been proven to have dangerous effects during animal or human testing; it may cause cancer or may harm certain organs or pregnant women
hazardous waste any waste that meets the Resource Conservation and Recovery Act (RCRA) criteria of ignitability, corrosiveness, reactivity, or toxicity
health care-associated infection (HAI) an infection that patients acquire during the course or receiving treatments for other conditions in an institutional setting
horizontal laminar flow hood an environment for the preparation of compounded sterile preparations in which air originating from the back of the hood moves forward across the hood into the room
hyperalimentation parenteral nutrition for individuals who are unable to eat solids or liquids
infection control policies and procedures put in place to minimize the risk of spreading infections in hospitals or other health care facilities
laminar airflow hood an environment for the preparation of sterile products
parenteral medications medications that bypass the digestive system but are intended for systemic action; the term parenteral most commonly describes medications given by injection, such as intravenously or intramuscularly
peripheral parenteral injection of a medication into the veins on the periphery of the body instead of into a central vein or artery
peripheral parenteral nutrition (PPN) intravenous nutrition administered through veins on the periphery of the body rather than through a central vein or artery
precipitate to separate from solution or suspension; a solid that emerges from a liquid solution
Primary engineering control (PEC) a device or zone that provides Class 5 environment for sterile compounding (i.e. hoods)
reconstituted a substance that has had a diluent (i.e. saline or sterile water) added to a powder
standard operating procedures (SOPs) written guidelines and criteria that list specific steps for various competencies
Standard Precautions (Universal Precautions) a set of standards that reduces the possibility of contamination and the risk of transmission infectious disease; these standards are used throughout a health care facility, including to prepare medications
sterile preparations a preparation that contains no living microorganisms
total parenteral nutrition (TPN) large volume intravenous nutrition administered through a central vein (i.e. subclavian vein), which allows for a higher concentration of solutions
United States Pharmacopeia <797> (USP <797>) Chapter 797, "Pharmaceutical Compounding-Sterile Preparations," of the USP National Formulary. It contains a set of enforceable sterile compounding standards; describes the guidelines, procedures, and compliance requirements for compounding sterile preparations; and sets the standards that apply to all settings in which sterile preparations are compounded
United States Pharmacopeia <800> (USP <800>) Chapter 800, "A new general chapter created to identify the requirements for receipt, storage, mixing, preparing, compounding, dispensing, and administration of hazardous drugs to protect the patient, health care personnel, and environment
vertical laminar flow hood an environment for the preparation of chemotherapeutic and other hazardous agents in which air originating from the roof of the hood moves downward (over the agent) and is captured in a vent on the floor of the hood
Created by: DbaileyC



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