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cardiovascular
BENCHMARK DRUGS
generic name | brand name | pharmacologic category | common indications | essential knowledge |
---|---|---|---|---|
lisinopril (PO) | Prinivil, Zestril | Angiotensin-converting enzyme (ACE) inhibitor | HTN, chronic HF, CAD | cough, hyperkalemia, angioedema, BBW: fetal toxicity (CI pregnancy) |
quinapril (PO) | Accupril | Angiotensin-converting enzyme (ACE) inhibitor | HTN, chronic HF, CAD | angioedema, BBW: fetal toxicity (CI pregnancy) |
ramipril (PO) | Altace | Angiotensin-converting enzyme (ACE) inhibitor | HTN, chronic HF, CAD | angioedema, BBW: fetal toxicity (CI pregnancy) |
irbesartan (PO) | Avapro | Angiotensin II receptor blocker (ARB) | HTN, CAD | hyperkaelmia, angioedema, BBW: fetal toxicity (CI pregnancy) |
losartan (PO) | Cozaar | Angiotensin II receptor blocker (ARB) | HTN, CAD | hyperkaelmia, angioedema, BBW: fetal toxicity (CI pregnancy) |
olmesartan (PO) | Benicar | Angiotensin II receptor blocker (ARB) | HTN, CAD | hyperkaelmia, angioedema, BBW: fetal toxicity (CI pregnancy) |
telmisartan (PO) | Micardis | Angiotensin II receptor blocker (ARB) | HTN, CAD | hyperkaelmia, angioedema, BBW: fetal toxicity (CI pregnancy) |
valsartan (PO) | Diovan | Angiotensin II receptor blocker (ARB) | HTN, chronic HF, CAD | hyperkaelmia, angioedema, BBW: fetal toxicity (CI pregnancy) |
amlodipine (PO) | Norvasc | Dihydropyridine calcium channel blocker (CCB) | HTN, CAD | edema (not all generic products are therapeutically equivalent) |
nifedipine (PO) | Procardia XL, Nifedical XL, Adalat CC | Dihydropyridine calcium channel blocker (CCB) | HTN, CAD | edema (not all generic products are therapeutically equivalent) |
nicardipine (PO, IV) | Cardene | Dihydropyridine calcium channel blocker (CCB) | Hypertensive crisis | flushing, HA, edema, hypotension |
diltiazem (PO, IV) | Cartia XT, Cardizem, Cardizem CD, Cardizem LA | Non-dihydropyridine calcium channel blocker (CCB) | AF (rate control), HTN, CAD | |
verapamil (PO) | Calan, Calan SR, Verelan | Non-dihydropyridine calcium channel blocker (CCB) | AF (rate control), HTN, CAD | |
chlorthalidone (PO) | Thalitone | Thiazide diuretic | HTN, volume overload | |
hydrochlorothiazide (PO) | Microzide | Thiazide diuretic | HTN, volume overload | |
metolazone (PO) | Zaroxolyn | Thiazide-like diuretic | HTN, volume overload | |
amlodipine and benazepril (PO) | Lotrel | -- | -- | |
lisinopril and hydrochlorothiazide (PO) | Prinzide | -- | -- | |
losartan and hydrochlorothiazide (PO) | Hyzaar | -- | -- | |
olmesartan and hydrochlorothiazide (PO) | Benicar-HCT | -- | -- | |
telmisartan and hydrochlorothiazide (PO) | Micardis HCT | -- | -- | |
triamterene and hydrochlorothiazide (PO) | Dyazide, Maxzide | -- | -- | |
valsartan and hydrochlorothiazide (PO) | Diovan-HCT | -- | -- | |
spironolactone (PO) | Aldactone | Potassium-sparing diuretic | HTN, chronic HF, ascites | |
bumetanide (PO, IV) | Bumex | Loop diuretic | Volume overload | |
furosemide (PO, IV) | Lasix | Loop diuretic | Volume overload | |
torsemide (PO) | Demadex | Loop diuretic | Volume overload | |
atenolol (PO) | Tenormin | Beta1-selective beta-blocker | AF (rate control), CAD, HTN | |
metoprolol tartrate (PO, IV) | Lopressor | Beta1-selective beta-blocker | AF (rate control), CAD, HTN | |
metoprolol succinate (PO) | Toprol-XL | Beta1-selective beta-blocker | Chronic HF, AF (rate control), CAD, HTN HTN | |
nebivolol (PO) | Bystolic | Beta1-selective beta-blocker | HTN | |
carvedilol (PO) | Coreg, Coreg CR | Non-selective beta-blocker | Chronic HF, AF (rate control), CAD, HTN | |
labetalol (PO, IV) | Trandate | Non-selective beta-blocker | PO: HTN, IV: hypertensive crisis | |
propranolol (PO) | Inderal LA, Inderal XL | Non-selective beta-blocker | HTN, CAD | |
clonidine (PO, transdermal) | PO: Catapres, Transdermal: Catapres-TTS | Alpha2 agonist | HTN, ADHD | |
hydralazine (PO, IV) | Apresoline | Direct arterial vasodilator | HTN | |
dobutamine (IV) | -- | Beta1 and beta2 agonist; inotrope | ADHF, cardiogenic shock | |
epinephrine (IV, IM, subQ) | Adrenalin | Beta1, beta2, and alpha1 agonist | Advanced cardiac life support, shock, anaphylaxis, bradycardia | |
norepinephrine (IV) | Levophed | Alpha1 agonist (predominantly), beta1 and beta2 agonist | Shock | |
bisoprolol and hydrochlorothiazide (PO) | Ziac | -- | -- | |
dabigatran (PO) | Pradaxa | Anticoagulant, direct thrombin inhibitor | AF (stroke prevention), VTE | |
apixaban (PO) | Eliquis | Anticoagulant, factor Xa inhibitor | AF (stroke prevention), VTE | |
rivaroxaban (PO) | Xarelto | Anticoagulant, factor Xa inhibitor | AF (stroke prevention), VTE | |
warfarin (PO) | Coumadin, Jantoven | Anticoagulant, vitamin K antagonist | AF (stroke prevention), VTE | |
enoxaparin (subQ) | Lovenox | Anticoagulant, low molecular weight heparin | ACS, VTE | |
heparin (IV, subQ) | --- | Anticoagulant | ACS, VTE | |
clopidogrel (PO) | Plavix | Antiplatelet agent | CAD, stroke | |
dipyridamole and aspirin (PO) | Aggrenox | Antiplatelet agent | Stroke | |
prasugrel (PO) | Effient | Antiplatelet agent | CAD | |
alteplase (intracatheter, IV) | Intracatheter: Cathflo, IV: Activase | Fibrinolytic | Intracatheter: catheter clearance. IV: STEMI, ischemic stroke, PE | |
amiodarone (PO, IV) | Cordarone, Pacerone | Antiarrhythmic | AF, ventricular fibrillation, ventricular tachycardia | |
sotalol (PO, IV) | Betapace | Antiarrhythmic | AF (rhythm control) | |
isosorbide mononitrate (PO) | Imdur | Vasodilator | CAD | |
nitroglycerin (PO, IV) | Nitrostat, NitroQuick | Vasodilator | CAD | |
colesevelam (PO) | Welchol | Bile acid sequestrant | Dyslipidemia | |
digoxin (PO, IV) | Digitek, Digox, Lanoxin | Cardiac glycoside | AF (rate control), chronic HF | |
ezetimibe (PO) | Zetia | Cholesterol absorption inhibitor | Dyslipidemia | |
fenofibrate (PO) | Tricor, Trilipix | Fibric acid derivative | Dyslipidemia | |
gemfibrozil (PO) | Lopid | Fibric acid derivative | Dyslipidemia | |
atorvastatin (PO) | Lipitor | HMG-CoA reductase inhibitor | Dyslipidemia, CAD, stroke | |
lovastatin (PO) | Mevacor | HMG-CoA reductase inhibitor | Dyslipidemia, CAD, stroke | |
pravastatin (PO) | Pravachol | HMG-CoA reductase inhibitor | Dyslipidemia, CAD, stroke | |
rosuvastatin (PO) | Crestor | HMG-CoA reductase inhibitor | Dyslipidemia, CAD, stroke | |
simvastatin (PO) | Zocor | HMG-CoA reductase inhibitor | Dyslipidemia, CAD, stroke | |
omega-3 fatty acids (PO) | Lovaza | Omega-3 fatty acids | Dyslipidemia | |
niacin (extended release) (PO) | Niaspan | Water-soluble vitamin | Dyslipidemia | |
ezetimibe and simvastatin (PO) | Vytorin | -- | -- | |
benazepril (PO) | Lotensin | Angiotensin-converting enzyme (ACE) inhibitor | HTN, chronic HF, CAD | angioedema, BBW: fetal toxicity (CI pregnancy) |
enalapril (PO) | Vasotec | Angiotensin-converting enzyme (ACE) inhibitor | HTN, chronic HF, CAD | angioedema, BBW: fetal toxicity (CI pregnancy) |