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Pharmacology CH2
| Term | Definition |
|---|---|
| Pruitis | itching sensation |
| Bioavailability | the degree to which a drug or other substance becomes available to the target tissue (site of action) after administration |
| Local Effect | an action of a drug that us confined to a specific part of the body |
| Lipid | a fatty molecule, an important constituent of cell membranes |
| Receptor | like a lock, only responds to a very specific "key"; when activated it triggers release of neurotransmitters or hormones |
| Agonist | stimulates a receptor |
| Dependence | a state in which a person's body has adapted physiologically and psychologically to a drug and cannot function without it |
| Systemic Effect | an action of a drug that has a generalize, all-inclusive effect on the body |
| Inhibition | the process whereby a drug blocks enzyme activity and impairs the metabolism of another drug |
| Elimination | metabolism + excretion |
| Induction | the strength by which a particular chemical messenger binds to its receptor site on a cell |
| Anaphylactic Shock | a severe allergic response resulting in immediate, life-threatening respiratory distress, usually followed by vascular collapse and shock and accompanied by hives |
| Maintenance Dose | amount of a drug administered at regular intervals to keep the blood concentration at a therapeutic level |
| Prophylactic | used to prevent infection or disease |
| Therapeutic Range | the optimum dosage, providing the best chance for successful therapy |
| Loading Dose | dose of medication given initially to reach a therapeutic blood level range quickly |
| Distribution | once in the bloodstream, how the drug gets to its site-of-action |
| Anatgonist | blocks stimulation of a receptor |
| Metabolism | occurs primarily in the liver; the breaking down of a drug into inactive or smaller molecules |
| Affinity | process of increasing concentration or activity of enzymes that effect the pharmacologic response to another drug |
| First-Pass Effect | all orally taken medications must undergo this process before entering circulation; the extent to which a drug is metabolized by the liver before reaching systemic circulation |
| Half-Life | the amount of time to dissolve in body fluids |
| Solubility | a drug's ability to dissolve in body fluids |
| Interaction | a change in the action of a drug caused by another drug, a food or another substance such as alcohol or nicotine |
| Antigen | a specific molecule that stimulates an immune response |
| Absorption | the process whereby a drug gets into the bloodstream |
Created by:
PharmacyTech2019
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