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Parkinson Disease

ch 17 nervous system

Parkinson disease progressive condition associated with the loss or deficiency of dopamine; drug therapy focuses on increasing dopamine and decreasing acetylcholine
TRAP symptoms tremor, rigidity, akinesia (loss of normal motor function), and postural instability
main therapies for PD levodopa plus carbidopa, dopamine agonists, and MAO-B inhibitors
five classes of PD drugs levodopa and carbidopa, dopamine agonists, MAO-B inhibitors, anticholinergics, and catechol-o-methyl tranferase (COMT) inhibtors
Sinemet carbidopa and levodopa *carbidopa and levodopa
Stalevo carbidopa, levodopa, and entacapone *carbidopa and levodopa
Requip ropinirole *dopamine agonists
Mirapex pramipexole *dopamine agonists
Azilect rasagiline *MAO-B inhibitors
Eldrepyl, Zelapar selegiline *MAO-B inhibitors
Cogentin benztropine *anticholinergics
Artane trihexyphenidyl *anticholinergics
Symmetrel amantadine *anticholinergics
Comtan entacapone *COMT inhibitors
Tasmar tolcapone *COMT inhibitors
Created by: DbaileyC



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