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Onco Pharm

Oncology

QuestionAnswer
Cyclophosphamide Cytoxan
Ifosfamide Ifex
Oxaliplatin Eloxatin
Temozolomide Temodar
Doxorubicin Adriamycin
Capecitabine Xeloda
Gemcitabine Gemzar
Pemetrexed Alimtra
Vinblastine Velban
Vincristine Oncovin
Paclitaxel Taxol
Paclitaxel (nanoparticle albumin bound) Abraxane
Docetaxel Taxotere
Topotecan Hycamtin
Irinotecan Camptosar
Cisplatin Platinol
Carboplatin Paraplatin
Oxaliplatin Eloxatin
Bicalutamide Casodex
Anastrozole Arimidex
Letrozole Femara
Erlotinib Tarceva
Imatinib Gleevec
Alemtuzumab Campath
Trastuzumab Herceptin
Bevacizumab Avastin
Rituximab Rituxan
Cetuximab Erbitux
Cytoxan Alkylating agent
Ifex Alkylating agent
Eloxatin Alkylating agent
Temodar Alkylating agent
Adriamycin Anthracycline
Xeloda Antimetabolite
Gemzar Antimetabolite
Alimtra Antimetabolite
Velban Vinca alkaloid
Oncovin Vinca alkaloid
Taxol Taxane
Abraxane Taxane
Taxotere Taxane
Hycamtin Camptothecins
Camptosar Camptothecins
Platinol Platinum compound
Paraplatin Platinum compound
Eloxatin Platinum compound
Casodex Antiandrogen
Arimidex Aromatase inhibitor
Femara Aromatase inhibitor
Tarceva EGFR-tyrosine kinase inhibitor
Gleevec Tyrosine kinase inhibitor
Campath Monoclonal antibody
Herceptin Monoclonal antibody
Avastin Monoclonal antibody
Rituxan Monoclonal antibody
Erbitux Monoclonal antibody
Alkylating agents MOA Transfer an alkyl group to DNA => disrupt DNA replication, causing strand breakage
Alkylating agent meds Cyclophosphamide. Busulfan. Carmustine (BCNU). Cisplatin. Carboplatin.
Antimetabolite MOA Inhibit enzymes in replication pathway for cells
Antimetabolite meds Cytarabine (ara-C). Gemcitabine. Fluorouracil (5FU). Methotrexate. Thioguanine.
Mitosis inhibitors MOA Bind to tubulin => prevent normal mitosis => disrupt cell division
Mitosis inhibitors meds Vincristine. Vinblastine. Paclitaxel. Docetaxel.
Hormone regulators MOA Tamoxifen: block estrogen receptors. Glucocorticoids: inhibit cytokine production. Leuprolide: mimic effects of gonadotropin-releasing hormone. Flutamide.
Intercalating agents MOA Bind to DNA and prevent synthesis of RNA or DNA
Intercalating agents meds Daunorubicin, doxorubicin, bleomycin
Created by: Abarnard