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ch 19, therapeutic agents for the musculoskeletal system, pharm tech

osteoporosis systemic skeletal disease characterized by low bone mass and bone tissue deterioration which leads to fragility and bone fracture
kyphosis bent over, stooped posture from vertebral fracture
drug classes to treat osteoporosis bisphosphonates, calcium supplements, parathyroid hormone analog, monoclonal antibody, misc agents
bisphosphonates treatment of choice for osteoporosis (inhibit resorption of calcium from bone)
Fosamax alendronate *bisphosphonates; PO once weekly
Boniva ibandronate *bisphosphonates; injected every 3 months
Actonel risedronate *bisphosphonates; PO once weekly
Reclast zoledronic acid *bisphosphonates; injected once yearly
Parathyroid Hormone Analogue Forteo / teriparatide *daily inj
Monoclonal antibody Prolia / denosumab; inhibits osteoclast activation
supplements to provide adequate calcium intake
Citracal + D calcium and vitamin D *supplement
Caltrate, Os-Cal, Tums calcium carbonate *supplement
Misc agents Miacalcin / calcitonin-salmon *calcitonin nasal spray; *ususally reserved for those unable to take bisphosphonates
Selective Estrogen Receptor Modulator (SERM) Evista / raloxifene *ususally reserved for those unable to take bisphosphonates
Created by: DbaileyC



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