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ch 18 therapeutic agents for the endocrine system, pharm tech

pancreas responsible for insulin and glucagon production and release
insulin important to transportation of glucose in the cell
diabetes mellitus chronic endocrine disease associated with hyperglycemia - blood glucose increase; too much sugar in the blood (high blood glucose).
Type 1 diabetes mellitus T1DM; inability of pancreas to synthesize and secrete insulin leading to insulin deficiency; absolute deficiency of insulin
symptoms of T1DM polyuria (frequent urination), polydipsia (excessive thirst), and polyphagia (excessive appetite); glucose loss via urination can cause dehydration, weight loss, fatigue, and extreme hunger
Type 2 diabetes mellitus insulin resistance, decreased ability of tissues to respond to insulin
risk factors for T2DM obesity, lack of exercise, HBP, history of GDM, older than 45, family history of T2DM, hyperlipidemia (elevated cholesterol levels)
GDM gestational diabetes; occurs during pregnancy and ususally returns to normal following birth
rapid acting insulin (within 15 min and lasts 4-6 hrs) Humalog/insulin lispro, Novolog/insulin aspart, Apidra/insulin glulisine
short acting insulin (within 1 hr and lasts 6-10 hrs) Humulin R, and Novolin R (all generically known as regular human insulin)
intermediate-acting insulin products (within 2 hrs and lasts 10-16 hrs) Humulin N / NPH insulin; Novolin N
long acting insulin (within 3-4 hrs and lasts 14-24 hours) Levemir or Levemir FlexPen / insulin detemir
long acting insulin (within 2-4 hrs and lasts up to 24 hrs) Lantus or Lantus Solostar / insulin glargine
Created by: DbaileyC



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