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adrenal gland
ch 18 therapeutic agents for the endocrine system, pharm tech
| Question | Answer |
|---|---|
| Cushing Disease | condition of excessive adrenocorticotropic hormone (ATCH) secretion from the anterior pituitary gland; condition of too much cortisol |
| drug therapy for Cushing Disease | Lysodren / mitotane or Metopirone / metyrapone |
| Lysodren | mitotane *Cushing disease |
| Metopirone | metyrapone *Cushing disease |
| hyperaldosteronism | excessive aldosterone secretion by the adrenal glands; aldosterone promotes the excretion of potassium and the retention of sodium and water resulting in hypertension and hypokalemia |
| drug therapy for hyperaldosteronism | hypertension medications and potassium supplements |
| Addison disease | associated with insufficient levels of adrenocorticotropic hormone (ACTH), cortisol deficiency, and sometimes aldosterone |
| drug therapy for Addison disease | corticosteroid replacement therapy; the medications are taken for life. The corticosteroid medication, which is usually taken orally (by mouth), replaces the cortisol and aldosterone the body is not producing. |
| fludrocortisone acetate | mineralocorticoid for Addison Disease which mimics the action of aldosterone |
| Cortef | hydrocortisone *glucocorticoids oral for Addison's |
| Medrol | methylprednisolone *glucocorticoids for Addison's |
| prednisone | anti-inflammatory, antipruritic, and vasoconstrictive effects *glucocorticoids for Addison's |