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Parkinson / Ner Sys

ch 17, therapeutic agents for the nervous system - pharm tech

QuestionAnswer
Parkinson disease progressive disorder associated with the loss or deficiency of dopamine, a neurotransmitter
TRAP symptoms tremor, rigidity, akinesia (for bradykinesia), and postural instability
Sinemet levodopa / carbidopa *levodopa / carbidopa class
Mirapex pramipexole *dopamine agonist
Requip ropinirole *dopamine agonist
Neupro rotigotine *dopamine agonist
Cogentin benztropine *anticholinergic
Artane trihexyphenidyl *anticholinergic
Symmetrel amantadine *anticholinergic
Catechol-O-Methyltransferase inhibitors COMT inhibitors; prevent the peripheral conversion of levodopa by the enzyme COMT
Comtan entacapone *COMT inhibitor
Tasmar tolcapone *COMT inhibitor
Monoamine Oxidase-B Inhibitors MAO-B Inhibitors; inhibition of MAO-B decreases the metabolism of dopamine in the CNS
Azilect rasagiline *MAO-B Inhibitors
Eldepryl or Zelapar selegiline *MAO-B Inhibitors
5 classes of PD medications levodopa/carbidopa, dopamine agonists, anticholinergics, COMT inhibitors, and MAO-B inhibitors
Created by: DbaileyC
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